Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21815977 | 0.89 | ALDH1A1 (0.57) | ALDH1A1HPGDMAPTCYP2C19CYP1A2 | |
| SCHEMBL8193680 | 0.84 | CYP1A2 (0.54) | ALDH1A1HPGDMAPTCYP2C19CYP1A2 | |
| SCHEMBL21816364 | 0.81 | CYP1A2 (0.46) | ALDH1A1HPGDMAPTCYP2C19CYP1A2 | |
| SCHEMBL28183105 | 0.80 | MYC (0.50) | ALDH1A1HPGDMAPTCYP2C19CYP1A2 | |
| SCHEMBL8189685 | 0.79 | ALDH1A1 (0.47) | ALDH1A1HPGDMAPTCYP2C19CYP1A2 | |
| SCHEMBL28323928 | 0.78 | CYP1A2 (0.43) | ALDH1A1HPGDMAPTCYP2C19CYP1A2 | |
| SCHEMBL21816252 | 0.78 | POLB (0.43) | ALDH1A1MAPTCYP2C19CYP1A2CYP2C9 | |
| SCHEMBL15284368 | 0.78 | ALDH1A1 (0.45) | ALDH1A1HPGDMAPTCYP2C19CYP1A2 | |
| SCHEMBL28574292 | 0.77 | CYP1A2 (0.46) | ALDH1A1HPGDMAPTCYP2C19CYP1A2 | |
| SCHEMBL29510565 | 0.77 | CYP1A2 (0.42) | ALDH1A1HPGDMAPTCYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000035916-A1 | HERBICIDAL 4-BENZOYLISOXAZOLES | AVENTIS CROPSCIENCE S.A. (FR) | 2000-06-22 | — | — | WO | disclosed |
| WO-1999003856-A1 | 4-BENZOYL-ISOXAZOLE- AND -PYRAZOLE DERIVATIVES AND 2-CYANO 1,3-DIONE DERIVATIVES AS HERBICIDES | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-28 | — | — | WO | disclosed |