Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8524846 | 0.80 | CTSS (0.40) | ALDH1A1KDM4EGAAMAPTSMN1; SMN2 | |
| SCHEMBL8525438 | 0.80 | HCRTR1 (0.45) | ALDH1A1CYP1A2CYP2C9CYP2C19HCRTR1 | |
| SCHEMBL8183530 | 0.79 | ALDH1A1 (0.54) | ALDH1A1KDM4EGAACYP1A2CYP2C9 | |
| SCHEMBL1826021 | 0.78 | SMN1; SMN2 (0.36) | ALDH1A1KDM4EGAACYP1A2CYP2C9 | |
| SCHEMBL8193680 | 0.77 | CYP1A2 (0.54) | ALDH1A1KDM4EGAACYP1A2CYP2C9 | |
| SCHEMBL8524776 | 0.76 | ALDH1A1 (0.41) | ALDH1A1KDM4EGAACYP1A2CYP2C9 | |
| SCHEMBL8193270 | 0.76 | ALDH1A1 (0.41) | ALDH1A1KDM4EGAACYP1A2CYP2C9 | |
| SCHEMBL8524662 | 0.75 | ALDH1A1 (0.44) | ALDH1A1KDM4EGAACYP1A2CYP2C9 | |
| SCHEMBL8489374 | 0.75 | CES2 (0.55) | ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL8524590 | 0.75 | MEN1 (0.46) | ALDH1A1KDM4EGAAHPGDNTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000035916-A1 | HERBICIDAL 4-BENZOYLISOXAZOLES | AVENTIS CROPSCIENCE S.A. (FR) | 2000-06-22 | — | — | WO | disclosed |
| WO-1999003856-A1 | 4-BENZOYL-ISOXAZOLE- AND -PYRAZOLE DERIVATIVES AND 2-CYANO 1,3-DIONE DERIVATIVES AS HERBICIDES | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-28 | — | — | WO | disclosed |