Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 2/20 | 0.31 |
| ▸ | MGAM | O43451 | 2/20 | 0.30 |
| ▸ | SI | P14410 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4953870 | 1.00 | STAT3 (0.31) | STAT3MGAMSI | |
| SCHEMBL4953874 | 0.86 | — | — | |
| SCHEMBL8045018 | 0.79 | OGA (0.37) | STAT3MGAMSI | |
| SCHEMBL662016 | 0.79 | OGA (0.37) | STAT3MGAMSI | |
| SCHEMBL6142431 | 0.79 | OGA (0.37) | STAT3MGAMSI | |
| SCHEMBL15445060 | 0.79 | STAT3 (0.33) | STAT3MGAMSI | |
| SCHEMBL6438566 | 0.79 | MGAM (0.30) | MGAMSI | |
| SCHEMBL12154805 | 0.79 | OGA (0.37) | STAT3MGAMSI | |
| SCHEMBL9999673 | 0.79 | OGA (0.37) | STAT3MGAMSI | |
| SCHEMBL13497166 | 0.79 | OGA (0.37) | STAT3MGAMSI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6121431-A | VIRICIDES AGAINST HUMAN IMMUNODEFICIENCY VIRUS AND HEPATITIS B VIRUS | MEDIVIR AB (SE) | 2000-09-19 | — | — | US | disclosed |
| US-5952500-A | VIRICIDES CAN BE USED IN THERAPEUTIC AND PROPHYLACTIC TREATMENT OF THE ACQUIRED IMMUNE DEFICIENCY SYNDROME (AIDS), INFECTIONS OF HUMAN IMMUNE DEFICIENCY VIRUSES, HEPATITIS B VIRUS, HERPES VIRUSES AND CANCER | MEDIVIR AB (SE) | 1999-09-14 | — | — | US | disclosed |
| US-5747473-A | L-nucleoside analogues and pharmaceutical compositions | MEDIVIR AB (SE) | 1998-05-05 | — | — | US | disclosed |
| US-5473063-A | Reacting 2,3-epoxy-butanediol/1,4-/(having protected hydroxyl groups) with an alpha allylic nucleophile yields 2-hydroxy-3-allyl-1,4-butanediol, then oxidatively cleaving the double bond, cyclization, halogenation, acetylation or oxyalkylation | MEDIVIR AB (SE) | 1995-12-05 | — | — | US | disclosed |
| EP-0554274-A1 | NUCLEOSIDE DERIVATIVES | Medivir Aktiebolag (SE) | 1993-08-11 | — | — | EP | disclosed |
| WO-1992006102-A1 | NUCLEOSIDE DERIVATIVES | MEDIVIR AB (SE) | 1992-04-16 | — | — | WO | disclosed |