SCHEMBL6142431

SCHEMBL6142431

COC1C[C@H](O)[C@H](CO)O1

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ OGA O60502 4/20 0.37
▸ PIM1 P11309 1/20 0.34
▸ CSNK2A2 P19784 1/20 0.34
▸ CSNK2B P67870 1/20 0.34
▸ CSNK2A1 P68400 1/20 0.34
▸ CSNK2A3 Q8NEV1 1/20 0.34
▸ STAT3 P40763 2/20 0.33
▸ PDE4D Q08499 2/20 0.33
▸ LGALS8 O00214 1/20 0.33
▸ LGALS3 P17931 1/20 0.33
▸ LGALS4 P56470 1/20 0.33
▸ MGAM O43451 2/20 0.33
▸ SI P14410 2/20 0.33
▸ PYGB P11216 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14228011 1.00 OGA (0.37) OGAPIM1CSNK2A2CSNK2BCSNK2A1
SCHEMBL2817760 1.00 OGA (0.37) OGAPIM1CSNK2A2CSNK2BCSNK2A1
SCHEMBL14199486 1.00 OGA (0.37) OGAPIM1CSNK2A2CSNK2BCSNK2A1
SCHEMBL662016 1.00 OGA (0.37) OGAPIM1CSNK2A2CSNK2BCSNK2A1
SCHEMBL13497166 1.00 OGA (0.37) OGAPIM1CSNK2A2CSNK2BCSNK2A1
SCHEMBL18533110 1.00 OGA (0.37) OGAPIM1CSNK2A2CSNK2BCSNK2A1
SCHEMBL9999673 1.00 OGA (0.37) OGAPIM1CSNK2A2CSNK2BCSNK2A1
SCHEMBL12154805 1.00 OGA (0.37) OGAPIM1CSNK2A2CSNK2BCSNK2A1
SCHEMBL8045018 1.00 OGA (0.37) OGAPIM1CSNK2A2CSNK2BCSNK2A1
SCHEMBL9843877 1.00 OGA (0.37) OGAPIM1CSNK2A2CSNK2BCSNK2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10865208-B2 ATG7 inhibitors and the uses thereof MILLENNIUM PHARMACEUTICALS, INC. (US) 2020-12-15 — — US disclosed
US-10865208-B2 ATG7 inhibitors and the uses thereof MILLENNIUM PHARMACEUTICALS, INC. (US) 2020-12-15 — — US disclosed
WO-2018089786-A1 ATG7 INHIBITORS AND THE USES THEREOF MILLENNIUM PHARMACEUTICALS, INC. (US) 2018-05-17 — — WO disclosed
US-20070083041-A1 Process for the preparation of 1-chloro-3,5-di-o-acyl-2-deoxy-l-ribofuranoside derivatives INALCO, S.P.A. (IT) 2007-04-12 — — US disclosed
US-20050228175-A1 Production method of 2-deoxy-L-ribose compound AJINOMOTO CO., INC. (JP) 2005-10-13 — — US disclosed
EP-1574515-A2 Production method of 2-deoxy-L-ribose compound Ajinomoto Co., Inc. (JP) 2005-09-14 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050228175-A1 Production method of 2-deoxy-L-ribose compound RNASEL, DERA, RPIA OGA 430/4885PIM1 1417/4885CSNK2A2 2894/4885
US-10865208-B2 ATG7 inhibitors and the uses thereof ATG7, BECN1, SQSTM1 OGA 3859/4885PIM1 2981/4885CSNK2A2 457/4885
US-20070083041-A1 Process for the preparation of 1-chloro-3,5-di-o-acyl-2-deoxy-l-ribofuranoside derivatives RNGTT, RNASEL, CPSF7 OGA 209/4885PIM1 2119/4885CSNK2A2 2378/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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