Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 8/20 | 0.65 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.65 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.57 |
| ▸ | AHCY | P23526 | 7/20 | 0.54 |
| ▸ | ADCY5 | O95622 | 3/20 | 0.53 |
| ▸ | PI4KA | P42356 | 1/20 | 0.52 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.52 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.52 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.52 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8174851 | 0.86 | ADORA2A (0.65) | ADORA2AADORA1ADORA2BAHCYADCY5 | |
| SCHEMBL8189896 | 0.81 | ADORA2A (0.68) | ADORA2AADORA1ADORA2BAHCYADCY5 | |
| SCHEMBL12948654 | 0.81 | ADORA2A (0.68) | ADORA2AADORA1ADORA2BAHCYADCY5 | |
| SCHEMBL8185730 | 0.80 | AHCY (0.64) | ADORA2AADORA1ADORA2BAHCYADCY5 | |
| SCHEMBL8185723 | 0.80 | AHCY (0.64) | ADORA2AADORA1ADORA2BAHCYADCY5 | |
| SCHEMBL8185728 | 0.80 | AHCY (0.64) | ADORA2AADORA1ADORA2BAHCYADCY5 | |
| SCHEMBL984944 | 0.79 | ADORA2A (1.00) | ADORA2AADORA1ADORA2BAHCYADCY5 | |
| SCHEMBL29459142 | 0.79 | ADORA2A (1.00) | ADORA2AADORA1ADORA2BAHCYADCY5 | |
| SCHEMBL11222112 | 0.79 | ADORA2A (0.80) | ADORA2AADORA1ADORA2BADCY5PI4KA | |
| Hydrochloric Acid SCHEMBL9193028 | 0.78 | ADORA2A (0.97) | ADORA2AADORA1ADORA2BAHCYADCY5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6017923-A | Carbo-acyclic nucleoside derivatives as antiviral and antineoplastic agents | HOECHST MARION ROUSSEL, INC. (US) | 2000-01-25 | — | — | US | disclosed |
| EP-0705264-B1 | CARBO-ACYCLIC NUCLEOSIDE DERIVATIVES AS ANTIVIRAL AND ANTINEOPLASTIC AGENTS | MERRELL PHARMA INC (US) | 1999-04-07 | — | — | EP | disclosed |
| EP-0705264-A1 | CARBO-ACYCLIC NUCLEOSIDE DERIVATIVES AS ANTIVIRAL AND ANTINEOPLASTIC AGENTS | MERRELL PHARMACEUTICALS INC. (US) | 1996-04-10 | — | — | EP | disclosed |
| WO-1995000515-A1 | CARBO-ACYCLIC NUCLEOSIDE DERIVATIVES AS ANTIVIRAL AND ANTINEOPLASTIC AGENTS | MERRELL PHARMACEUTICALS INC. (US) | 1995-01-05 | — | — | WO | disclosed |