Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL819340 | 0.80 | TLR4 (0.39) | TSHRLMNAHSD17B10ALDH1A1KDM4E | |
| SCHEMBL819318 | 0.79 | KDM4E (0.36) | LMNAHSD17B10ALDH1A1KDM4EGAA | |
| SCHEMBL818061 | 0.77 | ALDH1A1 (0.36) | TSHRLMNASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL818658 | 0.76 | ALDH1A1 (0.38) | TSHRTP53SMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL819729 | 0.75 | L3MBTL1 (0.40) | TSHRLMNATP53SMN1; SMN2HSD17B10 | |
| SCHEMBL31174918 | 0.75 | KCNH2 (0.41) | KCNH2TSHRLMNATP53SMN1; SMN2 | |
| SCHEMBL818754 | 0.74 | TSHR (0.38) | KCNH2TSHRLMNATP53SMN1; SMN2 | |
| SCHEMBL5964811 | 0.74 | ALDH1A1 (0.35) | HSD17B10ALDH1A1HPGDPTPN1CYP1A2 | |
| SCHEMBL818445 | 0.74 | TSHR (0.40) | TSHRLMNATP53HSD17B10ALDH1A1 | |
| SCHEMBL819482 | 0.73 | ALDH1A1 (0.42) | TSHRLMNATP53HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236908-B2 | Components and catalysts for the polymerization of olefins | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-08-07 | — | — | US | disclosed |
| US-20110269927-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-11-03 | — | — | US | disclosed |