Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8183965 | 0.84 | MAPT (0.54) | MAPK1MAPTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL8185127 | 0.83 | MAPT (0.59) | L3MBTL1MAPK1MAPTHSD17B10ALDH1A1 | |
| SCHEMBL8185122 | 0.83 | MAPT (0.59) | L3MBTL1MAPK1MAPTHSD17B10ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6981966 | 0.81 | L3MBTL1 (0.56) | L3MBTL1MAPK1MAPTTP53ALOX15 | |
| SCHEMBL8185140 | 0.79 | ALDH1A1 (0.63) | L3MBTL1SMN1; SMN2ALDH1A1KMT2AAKR1C3 | |
| SCHEMBL1144561 | 0.79 | P2RY12 (0.47) | MAPK1MAPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL1144558 | 0.79 | P2RY12 (0.47) | MAPK1MAPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL8325259 | 0.77 | L3MBTL1 (0.68) | L3MBTL1MAPK1MAPTTP53ALOX15 | |
| SCHEMBL632352 | 0.75 | L3MBTL1 (0.73) | L3MBTL1MAPK1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL21852720 | 0.75 | L3MBTL1 (0.64) | L3MBTL1MAPK1MAPTTP53ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6136781-A | NOVEL CYCLIC PENTAPEPTIDE OR SALTS EFFECTIVE AS MEDICINES FOR PREVENTING AND CURING SEX HORMONE-DEPENDENT CANCERS, PROSTATOMEGALY, ENDOMETRIOSIS, HYSTEROMYOMA, PUBERTY PRECOX, AMENORRHEAL SYNDROMES, MULTIOCULAR OVARIAN SYNDROMES, ALSO | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-10-24 | — | — | US | disclosed |