Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MELK | Q14680 | 5/20 | 0.57 |
| ▸ | FLT3 | P36888 | 2/20 | 0.57 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.56 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.56 |
| ▸ | MYLK | Q15746 | 1/20 | 0.56 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.56 |
| ▸ | DHODH | Q02127 | 3/20 | 0.56 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | PLAT | P00750 | 1/20 | 0.47 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8176062 | 0.80 | DHODH (0.55) | MELKFLT3CAMK2GCAMK2DMYLK | |
| SCHEMBL8185689 | 0.80 | NR1H4 (0.46) | DHODHNR1H4MEN1NPC1RAB9A | |
| SCHEMBL8186700 | 0.79 | NR1H4 (0.55) | MELKFLT3CAMK2GCAMK2DMYLK | |
| Hydrochloric Acid SCHEMBL7797660 | 0.79 | NR1H4 (0.45) | MELKFLT3CAMK2GCAMK2DMYLK | |
| Hydrochloric Acid SCHEMBL1189801 | 0.78 | TRPV1 (0.50) | MELKNR1H4MEN1NPC1RAB9A | |
| SCHEMBL14585871 | 0.77 | APOB (0.56) | MELKFLT3ROCK2 | |
| SCHEMBL11729866 | 0.77 | ROCK2 (0.77) | MELKMEN1NPC1RAB9AKMT2A | |
| SCHEMBL6645872 | 0.76 | MELK (0.48) | MELKFLT3CAMK2GCAMK2DMYLK | |
| SCHEMBL8369053 | 0.76 | NR1H4 (0.53) | MELKFLT3DHODHNR1H4MEN1 | |
| Hydrochloric Acid SCHEMBL1187983 | 0.75 | WEE1 (0.49) | MELKMEN1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6110934-A | Substituted benzamide derivatives and their use as anticonvulsants | SMITHKLINE BEECHAM P.L.C. (GB) | 2000-08-29 | — | — | US | disclosed |