Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.55 |
| ▸ | CA2 | P00918 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.32 |
| ▸ | PRKCA | P17252 | 1/20 | 0.32 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL819067 | 0.84 | ALDH1A1 (0.63) | ALDH1A1CYP3A4CA2LMNATSHR | |
| SCHEMBL819205 | 0.80 | ALDH1A1 (0.47) | ALDH1A1TSHRTDP1ATM | |
| SCHEMBL818062 | 0.79 | TSHR (0.49) | ALDH1A1CYP3A4LMNATSHRMAPK1 | |
| SCHEMBL817678 | 0.78 | TSHR (0.43) | ALDH1A1CYP3A4CA2LMNATSHR | |
| SCHEMBL817353 | 0.77 | ALDH1A1 (0.51) | ALDH1A1CYP3A4CA2LMNATSHR | |
| SCHEMBL818936 | 0.76 | ALDH1A1 (0.58) | ALDH1A1CYP3A4CA2LMNATSHR | |
| SCHEMBL817641 | 0.75 | ALDH1A1 (0.54) | ALDH1A1CYP3A4CA2LMNATSHR | |
| SCHEMBL226379 | 0.74 | ALDH1A1 (0.77) | ALDH1A1CYP3A4CA2LMNATSHR | |
| SCHEMBL818651 | 0.73 | ALDH1A1 (0.52) | ALDH1A1CYP3A4CA2LMNATSHR | |
| SCHEMBL10638818 | 0.72 | ALDH1A1 (0.64) | ALDH1A1CYP3A4CA2LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236908-B2 | Components and catalysts for the polymerization of olefins | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-08-07 | — | — | US | disclosed |
| US-20110269927-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-11-03 | — | — | US | disclosed |