Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.63 |
| ▸ | CA2 | P00918 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.57 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.57 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL818524 | 0.84 | ALDH1A1 (0.55) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| SCHEMBL818936 | 0.82 | ALDH1A1 (0.58) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| SCHEMBL817641 | 0.81 | ALDH1A1 (0.54) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| SCHEMBL226379 | 0.80 | ALDH1A1 (0.77) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| SCHEMBL818651 | 0.79 | ALDH1A1 (0.52) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| Bis(2-Ethylhexyl) Phthalate SCHEMBL29351619 | 0.78 | ALDH1A1 (1.00) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| SCHEMBL18069229 | 0.78 | LMNA (0.74) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| Bis(2-Ethylhexyl)Phthalate SCHEMBL29411299 | 0.78 | ALDH1A1 (1.00) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| Bis(2-Ethylhexyl)Phthalate SCHEMBL21733281 | 0.78 | ALDH1A1 (1.00) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| Bis(2-Ethylhexyl) Phthalate SCHEMBL2864306 | 0.78 | ALDH1A1 (1.00) | ALDH1A1CYP3A4CA2LMNAPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110269927-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-11-03 | — | — | US | disclosed |