Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.53 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.52 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.52 |
| ▸ | FPR1 | P21462 | 1/20 | 0.52 |
| ▸ | FPR3 | P25089 | 1/20 | 0.52 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.52 |
| ▸ | HTR1D | P28221 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5989500 | 0.85 | NPC1 (0.56) | KDM4EMAPTOPRM1OPRD1OPRK1 | |
| SCHEMBL5989548 | 0.83 | RXRA (0.59) | KDM4EMAPTOPRM1OPRD1OPRK1 | |
| SCHEMBL23358421 | 0.82 | PARP10 (0.50) | KDM4EMAPTOPRM1OPRD1OPRK1 | |
| SCHEMBL8782089 | 0.82 | RXRA (0.50) | KDM4EMAPTOPRM1OPRD1OPRK1 | |
| SCHEMBL20085626 | 0.82 | RXRA (0.50) | KDM4EMAPTOPRM1OPRD1OPRK1 | |
| SCHEMBL7097581 | 0.79 | L3MBTL1 (0.57) | KDM4EKMT2ALMNAL3MBTL1ALDH1A1 | |
| SCHEMBL8782235 | 0.78 | FFAR1 (0.47) | KDM4EMAPTOPRM1OPRD1OPRK1 | |
| SCHEMBL9283937 | 0.73 | CAPN1 (0.44) | KDM4EOPRL1HDAC6KMT2AMEN1 | |
| SCHEMBL3995720 | 0.73 | TSHR (0.50) | KDM4EMAPTFFAR4KMT2ALMNA | |
| SCHEMBL3997587 | 0.73 | FFAR1 (0.50) | KDM4EMAPTFFAR4LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008062296-A2 | NOP RECEPTOR AGONISTS FOR THE TREATMENT OF L-DOPA INDUCED DYSKINESIAS | UNIVERSITA' DEGLI STUDI DI FERRARA (IT) | 2008-05-29 | — | — | WO | disclosed |