Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 5/20 | 0.34 |
| ▸ | SPHK2 | Q9NRA0 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8184616 | 0.98 | SPHK1 (0.37) | SPHK1SPHK2ALDH1A1TDP1EPHX1 | |
| SCHEMBL8857990 | 0.86 | SPHK1 (0.41) | SPHK1SPHK2ALDH1A1TDP1EPHX1 | |
| SCHEMBL5704471 | 0.81 | SMN1; SMN2 (0.34) | SPHK1SPHK2ALDH1A1TDP1 | |
| SCHEMBL51206 | 0.78 | ALDH1A1 (0.46) | SPHK1SPHK2ALDH1A1EPHX1 | |
| SCHEMBL8185674 | 0.78 | SPHK1 (0.41) | SPHK1SPHK2ALDH1A1TDP1EPHX1 | |
| SCHEMBL7110587 | 0.76 | ALDH1A1 (0.50) | SPHK1SPHK2ALDH1A1EPHX1 | |
| SCHEMBL11809342 | 0.76 | ALDH1A1 (0.50) | SPHK1SPHK2ALDH1A1EPHX1 | |
| SCHEMBL11688324 | 0.76 | ALDH1A1 (0.50) | SPHK1SPHK2ALDH1A1EPHX1 | |
| SCHEMBL8855730 | 0.76 | ALDH1A1 (0.50) | SPHK1SPHK2ALDH1A1EPHX1 | |
| SCHEMBL5685367 | 0.76 | ALDH1A1 (0.50) | SPHK1SPHK2ALDH1A1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6048991-A | Preparation of epoxides | BASF AKTIENGESELLSCHAFT (DE) | 2000-04-11 | — | — | US | disclosed |