SCHEMBL7110587

SCHEMBL7110587

CCCCCCC1OC1CCCCCC

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.50
TSHR P16473 1/20 0.47
THRB P10828 1/20 0.47
EPHX1 P07099 1/20 0.46
SPHK1 Q9NYA1 7/20 0.45
SPHK2 Q9NRA0 6/20 0.45
POLB P06746 1/20 0.39
FASN P49327 1/20 0.39
DAGLA Q9Y4D2 1/20 0.38
CYP1A2 P05177 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11687578 1.00 ALDH1A1 (0.50) ALDH1A1TSHRTHRBEPHX1SPHK1
SCHEMBL11688324 1.00 ALDH1A1 (0.50) ALDH1A1TSHRTHRBEPHX1SPHK1
SCHEMBL8727383 1.00 ALDH1A1 (0.50) ALDH1A1TSHRTHRBEPHX1SPHK1
SCHEMBL8855730 1.00 ALDH1A1 (0.50) ALDH1A1TSHRTHRBEPHX1SPHK1
SCHEMBL5685367 1.00 ALDH1A1 (0.50) ALDH1A1TSHRTHRBEPHX1SPHK1
SCHEMBL11689950 1.00 ALDH1A1 (0.50) ALDH1A1TSHRTHRBEPHX1SPHK1
SCHEMBL8855829 1.00 ALDH1A1 (0.50) ALDH1A1TSHRTHRBEPHX1SPHK1
SCHEMBL11809342 1.00 ALDH1A1 (0.50) ALDH1A1TSHRTHRBEPHX1SPHK1
SCHEMBL8855705 1.00 ALDH1A1 (0.50) ALDH1A1TSHRTHRBEPHX1SPHK1
SCHEMBL8855707 1.00 ALDH1A1 (0.50) ALDH1A1TSHRTHRBEPHX1SPHK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0612835-A2 Refrigerating machine oil composition IDEMITSU KOSAN COMPANY LIMITED (JP) 1994-08-31 EP claimed
WO-2023235556-A2 EPOXIDE COMPOUNDS, METHODS OF PREPARATIONS AND USES THEREOF ZSCHIMMER & SCHWARZ, INC. (US) 2023-12-07 WO disclosed
US-11795153-B1 Epoxide compounds, methods of preparations and uses thereof ZSCHIMMER & SCHWARZ, INC. (US) 2023-10-24 US disclosed
US-11795153-B1 Epoxide compounds, methods of preparations and uses thereof ZSCHIMMER & SCHWARZ, INC. (US) 2023-10-24 US disclosed
EP-2470628-B1 MULTI-GRADE ENGINE OIL FORMULATIONS COMPRISING AN ESTER COMPONENT CHEVRON USA INC (US) 2017-08-30 EP disclosed
EP-2250241-B1 SYNTHESIS OF DIESTER-BASED BIOLUBRICANTS FROM EPOXIDES CHEVRON USA INC (US) 2016-12-21 EP disclosed
US-9109238-B2 Synthesis of diester-based lubricants from enzymatically-directed epoxides CHEVRON U.S.A. INC. (US) 2015-08-18 US disclosed
US-20150140623-A1 Synthesis of Diester-Based Lubricants from Enzymatically-Directed Epoxides NOVOZYMES A/S (DK) 2015-05-21 US disclosed
US-8795547-B2 Refrigeration oil from gas-to-liquid-derived and bio-derived triesters CHEVRON U.S.A. INC. (US) 2014-08-05 US disclosed
US-8585919-B2 Refrigeration oil from gas-to-liquid derived and bio-derived diesters CHEVRON U.S.A. INC. (US) 2013-11-19 US disclosed
US-6348608-B1 ADDING OXIDIZING AGENT TO REACTION SOLUTION COMPRISING CHIRAL CYCLIC ENANTIOMERICALLY ENRICHED KETONE AND OLEFIN UNDER CONDITIONS EFFECTIVE TO GENERATE ENANTIOMERICALLY ENRICHED EPOXIDE, SEPARATING EPOXIDE FROM REACTION SOLUTION COLORADO STATE UNIVERSITY RESEARCH FOUNDATION 2002-02-19 US disclosed
EP-1021426-A4 CATALYTIC ASYMMETRIC EPOXIDATION UNIV COLORADO STATE RES FOUND (US) 2000-07-26 EP disclosed
EP-1021426-A1 CATALYTIC ASYMMETRIC EPOXIDATION COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2000-07-26 EP disclosed
EP-0979220-A1 SINGLE-STAGE METHOD FOR PRODUCING ALPHA-HYDROXY ETHERS BY OXIDIZING C=C-UNSATURATED COMPOUNDS WITH HYDROPEROXIDES SASOL Germany GmbH (DE) 2000-02-16 EP disclosed
WO-1998047844-A1 SINGLE-STAGE METHOD FOR PRODUCING α-HYDROXY ETHERS BY OXIDIZING C=C-UNSATURATED COMPOUNDS WITH HYDROPEROXIDES RWE-DEA Aktiengesellschaft für Mineraloel und Chemie (DE) 1998-10-29 WO disclosed
WO-1998015544-A1 CATALYTIC ASYMMETRIC EPOXIDATION COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) 1998-04-16 WO disclosed
US-5454963-A Refrigerating machine oil composition containing an epoxy compound IDEMITSU KOSAN CO., LTD. (JP) 1995-10-03 US disclosed
EP-0612835-A2 Refrigerating machine oil composition IDEMITSU KOSAN COMPANY LIMITED (JP) 1994-08-31 EP disclosed
US-4013723-A REACTION OF AN OXIRANE WITH HYDROGEN PEROXIDE BAYER AKTIENGESELLSCHAFT (DT) 1977-03-22 US disclosed
US-3974224-A HYDROGEN PEROXIDE BAYER AKTIENGESELLSCHAFT (DT) 1976-08-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11795153-B1 Epoxide compounds, methods of preparations and uses thereof EPHX2, EPHX1, VKORC1 ALDH1A1 315/4885TSHR 4765/4885THRB 4660/4885
US-20150140623-A1 Synthesis of Diester-Based Lubricants from Enzymatically-Directed Epoxides DGAT2, ADH1A, ELOVL1 ALDH1A1 39/4885TSHR 3247/4885THRB 2739/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.