Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.47 |
| ▸ | DHODH | Q02127 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8184192 | 0.94 | NR1H4 (0.45) | MEN1KMT2ANR1H4DHODHMAPT | |
| Hydrochloric Acid SCHEMBL8187880 | 0.93 | NR1H4 (0.45) | MEN1KMT2ANR1H4DHODHMAPT | |
| SCHEMBL7797955 | 0.85 | ALDH1A1 (0.48) | MEN1KMT2ANR1H4DHODHMAPT | |
| SCHEMBL7801359 | 0.84 | ABHD6 (0.46) | MEN1KMT2ANR1H4DHODHMAPT | |
| SCHEMBL7993333 | 0.83 | NR1H4 (0.45) | MEN1KMT2ANR1H4DHODHMAPT | |
| SCHEMBL8185689 | 0.83 | NR1H4 (0.46) | MEN1KMT2ANR1H4DHODHMAPT | |
| Hydrochloric Acid SCHEMBL7797660 | 0.82 | NR1H4 (0.45) | MEN1KMT2ANR1H4DHODHMAPT | |
| SCHEMBL6295054 | 0.81 | GPR6 (0.47) | MEN1KMT2ANR1H4DHODHMAPT | |
| SCHEMBL8176766 | 0.80 | ALDH1A1 (0.50) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8184284 | 0.80 | ALDH1A1 (0.49) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6110934-A | Substituted benzamide derivatives and their use as anticonvulsants | SMITHKLINE BEECHAM P.L.C. (GB) | 2000-08-29 | — | — | US | disclosed |