Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL817911 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL272678 | 0.73 | NPC1 (0.30) | NPC1HPGDMAPK1HTTRAB9A | |
| Hydrochloric Acid SCHEMBL722079 | 0.70 | NPC1 (0.30) | NPC1HPGDMAPK1HTTRAB9A | |
| Hydrochloric Acid SCHEMBL8434866 | 0.69 | NPC1 (0.31) | NPC1HPGDMAPK1HTTRAB9A | |
| Hydrochloric Acid SCHEMBL2142111 | 0.69 | NPC1 (0.31) | NPC1HPGDMAPK1HTTRAB9A | |
| Hydrochloric Acid SCHEMBL27825002 | 0.69 | NPC1 (0.31) | NPC1HPGDMAPK1HTTRAB9A | |
| Hydrochloric Acid SCHEMBL3802951 | 0.69 | NPC1 (0.34) | NPC1HPGDMAPK1HTTRAB9A | |
| Hydrochloric Acid SCHEMBL4534414 | 0.69 | NPC1 (0.31) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL1539590 | 0.69 | NPC1 (0.36) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL1025348 | 0.69 | NPC1 (0.32) | NPC1HPGDMAPK1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2760958-B1 | SYSTEMS, METHODS AND COMPOSITIONS FOR PRODUCTION OF TIE-LAYER ADHESIVES | EQUISTAR CHEM LP (US) | 2020-08-12 | — | — | EP | disclosed |
| EP-2673315-B1 | POLYETHYLENE FILMS | EQUISTAR CHEM LP (US) | 2019-03-20 | — | — | EP | disclosed |
| EP-1943281-B1 | HYBRID CATALYST SYSTEMS SUPPORTED ON MAGNESIUM HALIDE | BASELL POLYOLEFINE GMBH (DE) | 2017-09-20 | — | — | EP | disclosed |
| US-9676971-B2 | Systems, methods and compositions for production of tie-layer adhesives | EQUISTAR CHEMICALS, LP (US) | 2017-06-13 | — | — | US | disclosed |
| US-20160222257-A1 | SYSTEMS, METHODS AND COMPOSITIONS FOR PRODUCTION OF TIE-LAYER ADHESIVES | EQUISTAR CHEMICALS, LP (US) | 2016-08-04 | — | — | US | disclosed |
| US-9321945-B2 | Systems, methods and compositions for production of tie-layer adhesives | EQUISTAR CHEMICALS, LP (US) | 2016-04-26 | — | — | US | disclosed |
| CN-102105497-B | The method changed between incompatible olefin polymerization catalyst system | BASELL POLYOLEFINE GMBH (DE) | 2016-02-24 | — | — | CN | disclosed |
| US-9029478-B2 | High clarity polyethylene films | EQUISTAR CHEMICALS, LP (US) | 2015-05-12 | — | — | US | disclosed |
| EP-2114567-B1 | IRON COMPLEXES AND THEIR USE IN POLYMERIZATION PROCESSES | BASELL POLYOLEFINE GMBH (DE) | 2015-04-15 | — | — | EP | disclosed |
| US-8865834-B2 | Adhesive polymer composition | BASELL POLYOLEFINE GMBH (DE) | 2014-10-21 | — | — | US | disclosed |
| US-20090306299-A1 | Multimodal polyethylene composition, mixed catalyst and process for preparing the composition | BASELL POLYOLEFINE GMBH (DE) | 2009-12-10 | — | — | US | disclosed |
| EP-2114567-A1 | IRON COMPLEXES AND THEIR USE IN POLYMERIZATION PROCESSES | Basell Polyolefine GmbH (DE) | 2009-11-11 | — | — | EP | disclosed |
| EP-2102282-A2 | MULTIMODAL POLYETHYLENE COMPOSITION, MIXED CATALYST AND PROCESS FOR PREPARING THE COMPOSITION | Basell Polyolefine GmbH (DE) | 2009-09-23 | — | — | EP | disclosed |
| US-20090118445-A1 | Hybrid Catalyst Systems Supported On Magnesium Halide | BASELL POLYOLOLINE GMBH (DE) | 2009-05-07 | — | — | US | disclosed |
| EP-1753794-B9 | POLYETHYLENE AND CATALYST COMPOSITION FOR ITS PREPARATION | BASELL POLYOLEFINE GMBH (DE) | 2009-03-04 | — | — | EP | disclosed |
| US-20080286509-A1 | Polyethylene and Catalyst Composition for Its Preparation | BASELL POLYOLEFINE GMBH (DE) | 2008-11-20 | — | — | US | disclosed |
| WO-2008107135-A1 | IRON COMPLEXES AND THEIR USE IN POLYMERIZATION PROCESSES | BASELL POLYOLEFINE GMBH (DE) | 2008-09-12 | — | — | WO | disclosed |
| WO-2008077530-A2 | MULTIMODAL POLYETHYLENE COMPOSITION, MIXED CATALYST AND PROCESS FOR PREPARING THE COMPOSITION | BASELL POLYOLEFINE GMBH (DE) | 2008-07-03 | — | — | WO | disclosed |
| US-20070255033-A1 | Polyethylene for Injection Moldings | BASELL POYOLEFINE GMBH (DE) | 2007-11-01 | — | — | US | disclosed |
| US-20070213205-A1 | Polyethylene and Catalyst Composition for its Preparation | BASELL POLYOLEFINE GMBH (DE) | 2007-09-13 | — | — | US | disclosed |