Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7626373 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL6902633 | 0.79 | CES2 (0.36) | — | |
| Hydrochloric Acid SCHEMBL27482570 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL818600 | 0.70 | NPC1 (0.30) | NPC1HPGDMAPK1HTTRAB9A | |
| Hydrochloric Acid SCHEMBL272678 | 0.70 | NPC1 (0.30) | NPC1HPGDMAPK1HTTRAB9A | |
| Hydrochloric Acid SCHEMBL3802951 | 0.69 | NPC1 (0.34) | NPC1HPGDMAPK1HTTRAB9A | |
| Hydrochloric Acid SCHEMBL2142111 | 0.69 | NPC1 (0.31) | NPC1HPGDMAPK1HTTRAB9A | |
| Hydrochloric Acid SCHEMBL27825002 | 0.69 | NPC1 (0.31) | NPC1HPGDMAPK1HTTRAB9A | |
| Hydrochloric Acid SCHEMBL4534414 | 0.69 | NPC1 (0.31) | NPC1HPGDMAPK1HTTRAB9A | |
| Hydrochloric Acid SCHEMBL8434866 | 0.69 | NPC1 (0.31) | NPC1HPGDMAPK1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8357765-B2 | Process for producing catalyst component for addition polymerization | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-01-22 | — | — | US | disclosed |
| US-20120264889-A1 | PRODUCTION PROCESS OF OLEFIN POLYMERIZATION CATALYST AND OLEFIN POLYMER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-10-18 | — | — | US | disclosed |
| US-8288490-B2 | Process for producing catalyst component for addition polymerization | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-10-16 | — | — | US | disclosed |
| US-8247510-B2 | Copolymer and production process thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-08-21 | — | — | US | disclosed |
| US-20120053306-A1 | PROCESS FOR PRODUCING CATALYST COMPONENT FOR ADDITION POLYMERIZATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-03-01 | — | — | US | disclosed |
| US-20120053311-A1 | PROCESS FOR PRODUCING CATALYST COMPONENT FOR ADDITION POLYMERIZATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-03-01 | — | — | US | disclosed |
| US-20110288250-A1 | Copolymer and Production Process Thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-11-24 | — | — | US | disclosed |
| US-8044159-B2 | Homopolymer and copolymer, and production process thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-10-25 | — | — | US | disclosed |
| WO-2011074688-A1 | PRODUCTION PROCESS OF OLEFIN POLYMERIZATION CATALYST AND OLEFIN POLYMER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-06-23 | — | — | WO | disclosed |
| US-7964691-B2 | 5,5-diallyl-2,2-dimethyl-1,3-dioxane as monomer units; polymerization catalysts; heat resistance | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-06-21 | — | — | US | disclosed |
| US-20020143124-A1 | Homogeneous type solid catalyst component or homogeneous type solid catalyst, process for production thereof and process for producing addition polymer with the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-10-03 | — | — | US | disclosed |
| US-20020077432-A1 | Copolymerization of olefins | BENNETT ALISON MARGARET ANNE (US) | 2002-06-20 | — | — | US | disclosed |
| US-6384144-B1 | TWO DIFFERENT POLYMERIZATION CATALYSTS OF WHICH A) AT LEAST ONE IS A POLYMERIZATION CATALYST BASED ON AN EARLY TRANSITION METAL COMPONENT AND B) AT LEAST ONE IS A POLYMERIZATION CATALYST BASED ON A LATE TRANSITION METAL COMPONENT. | BASELL POLYPROPYLEN GMBH (DE) | 2002-05-07 | — | — | US | disclosed |
| US-20020026012-A1 | CATALYST COMPOSITION | EQUISTAR CHEMICALS, LP | 2002-02-28 | — | — | US | disclosed |
| US-20010041775-A1 | Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-11-15 | — | — | US | disclosed |
| US-20010020075-A1 | Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-09-06 | — | — | US | disclosed |
| US-6262196-B1 | AS POLYMERIZATION CATALYST IN POLYMERIZATION OF OLEFINS | TARGOR GMBH (DE) | 2001-07-17 | — | — | US | disclosed |
| EP-1113025-A2 | Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-07-04 | — | — | EP | disclosed |
| EP-1113026-A2 | Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-07-04 | — | — | EP | disclosed |
| EP-0985673-A2 | Modified aluminium oxy compound, polymerization catalyst and process for producing olefin polymer and alkenyl aromatic hydrocarbon polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-03-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053306-A1 | PROCESS FOR PRODUCING CATALYST COMPONENT FOR ADDITION POLYMERIZATION | PPOX, SOD1, AP1M1 | NPC1 4275/4885HPGD 1551/4885MAPK1 2406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.