Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 3/20 | 0.35 |
| ▸ | HTR2B | P41595 | 3/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 3/20 | 0.33 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.30 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8189436 | 0.97 | DGAT1 (0.39) | HTR2CDGAT1HTR2AHTR2BAURKA | |
| SCHEMBL8191394 | 0.96 | DGAT1 (0.41) | HTR2CDGAT1HTR2AHTR2BAURKA | |
| SCHEMBL8176685 | 0.94 | HTR2C (0.36) | HTR2CDGAT1HTR2AHTR2BAURKA | |
| SCHEMBL8176828 | 0.73 | HTR2C (0.41) | HTR2CHTR2AHTR2BACVR1KMT2A | |
| SCHEMBL6627873 | 0.72 | KDM4E (0.46) | KDRKMT2A | |
| SCHEMBL8187595 | 0.71 | HTR2C (0.39) | HTR2CDGAT1HTR2AHTR2BKDR | |
| SCHEMBL8177651 | 0.71 | HTR2C (0.42) | HTR2CDGAT1HTR2AHTR2BKDR | |
| SCHEMBL29711807 | 0.70 | KDR (0.39) | HTR2CDGAT1HTR2AHTR2BKDR | |
| SCHEMBL8177215 | 0.70 | HTR2C (0.41) | HTR2CHTR2AHTR2BACVR1KMT2A | |
| SCHEMBL8188129 | 0.70 | KMT2A (0.50) | HTR2CHTR2AHTR2BACVR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057330-A | USEFUL FOR THE PREVENTION AND TREATMENT OF A RESPIRATORY DISEASES REPRESENTED BY ASTHMA | POLA CHEMICAL INDUSTRIES, INC. (JP) | 2000-05-02 | — | — | US | disclosed |