Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8181076 | 0.89 | CSNK2A1 (0.32) | CSNK2A1PDE4BKDM4E | |
| SCHEMBL8194573 | 0.85 | ADAMTS4 (0.34) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8181070 | 0.84 | KDM4E (0.38) | CSNK2A1KDM4ENPC1ALDH1A1HPGD | |
| SCHEMBL8253078 | 0.79 | KDM4E (0.30) | KDM4EALDH1A1 | |
| SCHEMBL8181072 | 0.78 | KDM4E (0.38) | CSNK2A1PDE4BKDM4ENPC1ALDH1A1 | |
| SCHEMBL8194570 | 0.74 | MAPK1 (0.41) | KDM4EALDH1A1HPGDKMT2AHSD17B10 | |
| SCHEMBL8191599 | 0.74 | PIM1 (0.39) | KDM4EALDH1A1HPGDKMT2AHSD17B10 | |
| SCHEMBL8189987 | 0.74 | ADAMTS4 (0.32) | — | |
| SCHEMBL8247063 | 0.73 | LCK (0.36) | KDM4ENPC1ALDH1A1HPGDRAB9A | |
| SCHEMBL8247384 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008063671-A2 | HETEROBICYCLIC METALLOPROTEASE INHIBITORS | ALANTOS PHARMACEUTICALS HOLDING, INC. (US) | 2008-05-29 | — | — | WO | disclosed |