Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8194573 | 0.89 | ADAMTS4 (0.34) | ADAMTS4MMP3MMP13 | |
| SCHEMBL8181076 | 0.85 | CSNK2A1 (0.32) | — | |
| SCHEMBL8247345 | 0.77 | LCK (0.38) | ADAMTS4MMP3MMP13 | |
| SCHEMBL4258587 | 0.76 | KDM4E (0.39) | ADAMTS4MMP3MMP13 | |
| SCHEMBL8186296 | 0.74 | CSNK2A1 (0.34) | — | |
| SCHEMBL10164456 | 0.74 | LCK (0.38) | — | |
| SCHEMBL8175876 | 0.73 | PIM1 (0.36) | — | |
| SCHEMBL13164207 | 0.71 | KDM4E (0.41) | ADAMTS4MMP3MMP13 | |
| SCHEMBL8247063 | 0.69 | LCK (0.36) | — | |
| SCHEMBL8181072 | 0.69 | KDM4E (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008063671-A2 | HETEROBICYCLIC METALLOPROTEASE INHIBITORS | ALANTOS PHARMACEUTICALS HOLDING, INC. (US) | 2008-05-29 | — | — | WO | disclosed |