Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 10/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
| ▸ | CTSB | P07858 | 2/20 | 0.42 |
| ▸ | CTSS | P25774 | 2/20 | 0.42 |
| ▸ | CTSV | O60911 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8189552 | 0.86 | CCR3 (0.59) | CCR3KMT2AMAPTGAACTSL | |
| SCHEMBL8173772 | 0.82 | CCR3 (0.58) | CCR3CTSLCTSBCTSSCTSV | |
| SCHEMBL8194664 | 0.81 | TP53 (0.44) | CCR3MEN1KMT2ALMNAMAPT | |
| SCHEMBL8195128 | 0.81 | CCR3 (0.55) | CCR3GAACTSLCTSBCTSS | |
| SCHEMBL8195130 | 0.81 | CCR3 (0.55) | CCR3GAACTSLCTSBCTSS | |
| SCHEMBL8014171 | 0.81 | CCR3 (0.66) | CCR3MEN1KMT2ACTSB | |
| SCHEMBL7608481 | 0.81 | CCR3 (0.66) | CCR3MEN1KMT2ACTSB | |
| SCHEMBL8186345 | 0.80 | CCR3 (0.46) | CCR3MEN1KMT2ALMNAMAPT | |
| SCHEMBL8192895 | 0.79 | CCR3 (0.59) | CCR3MEN1KMT2AMAPTCRHBP | |
| SCHEMBL8185569 | 0.79 | CCR3 (0.58) | CCR3MEN1KMT2ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000027843-A1 | CCR-3 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-05-18 | — | — | WO | claimed |
| WO-2000027843-A1 | CCR-3 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-05-18 | — | — | WO | disclosed |