Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 10/20 | 0.59 |
| ▸ | CTSB | P07858 | 2/20 | 0.46 |
| ▸ | CTSV | O60911 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8195128 | 0.88 | CCR3 (0.55) | CCR3CTSBCTSVCTSLCTSS | |
| SCHEMBL8195130 | 0.88 | CCR3 (0.55) | CCR3CTSBCTSVCTSLCTSS | |
| SCHEMBL8173772 | 0.88 | CCR3 (0.58) | CCR3CTSBCTSVCTSLCTSS | |
| SCHEMBL7608481 | 0.87 | CCR3 (0.66) | CCR3CTSBCAPN1KMT2A | |
| SCHEMBL8014171 | 0.87 | CCR3 (0.66) | CCR3CTSBCAPN1KMT2A | |
| SCHEMBL8186342 | 0.86 | CCR3 (0.61) | CCR3CTSBCTSVCTSLCTSS | |
| SCHEMBL8010973 | 0.85 | CCR3 (0.61) | CCR3CTSBCTSVCTSLCTSS | |
| SCHEMBL8010976 | 0.85 | CCR3 (0.61) | CCR3CTSBCTSVCTSLCTSS | |
| SCHEMBL8010528 | 0.85 | CCR3 (0.61) | CCR3CTSBCTSVCTSLCTSS | |
| SCHEMBL8024409 | 0.85 | CCR3 (0.61) | CCR3CTSBCTSVCTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000027843-A1 | CCR-3 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-05-18 | — | — | WO | claimed |
| WO-2000027843-A1 | CCR-3 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-05-18 | — | — | WO | disclosed |