Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 4/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | JUN | P05412 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL818933 | 0.90 | CA9 (0.42) | CA9CA12CA1CA2RAB9A | |
| SCHEMBL819232 | 0.77 | CA9 (0.33) | CA9CA12CA1CA2 | |
| SCHEMBL26757094 | 0.75 | ALDH1A1 (0.49) | CA9CA12CA1CA2RAB9A | |
| SCHEMBL18391988 | 0.74 | CA9 (0.53) | CA9CA12CA1CA2RAB9A | |
| SCHEMBL1786408 | 0.74 | RAB9A (0.43) | CA9CA12CA1CA2RAB9A | |
| SCHEMBL29311930 | 0.73 | CA9 (0.49) | CA9CA12CA1CA2ALDH1A1 | |
| SCHEMBL17487041 | 0.72 | ALDH1A1 (0.49) | CA9CA12CA1CA2RAB9A | |
| SCHEMBL26223788 | 0.72 | CA9 (0.48) | CA9CA12CA1CA2RAB9A | |
| SCHEMBL14726193 | 0.72 | ALDH1A1 (0.46) | CA9CA12CA1POLBALDH1A1 | |
| SCHEMBL20286680 | 0.71 | MAPK1 (0.44) | CA9CA12CA1CA2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8664335-B2 | Thermally crosslinked polymeric compositions and methods of making the same | GEORGIA TECH RESEARCH CORPORATION (US) | 2014-03-04 | — | — | US | disclosed |
| US-20110269915-A1 | THERMALLY CROSSLINKED POLYMERIC COMPOSITIONS AND METHODS OF MAKING THE SAME | GEORGIA TECH RESEARCH CORPORATION (US) | 2011-11-03 | — | — | US | disclosed |