Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.48 |
| ▸ | SI | P14410 | 1/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.48 |
| ▸ | TOP1 | P11387 | 4/20 | 0.48 |
| ▸ | CYCS | P99999 | 3/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.46 |
| ▸ | TERT | O14746 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8187553 | 0.99 | ABCG2 (0.48) | ABCG2GAAMGAMSIMGAM2 | |
| SCHEMBL14350953 | 0.95 | ABCG2 (0.48) | ABCG2GAAMGAMSIMGAM2 | |
| SCHEMBL32662346 | 0.89 | NOX1 (0.49) | ABCG2GAATOP1CYCSENPP2 | |
| SCHEMBL2694939 | 0.89 | NOX1 (0.49) | ABCG2GAATOP1CYCSENPP2 | |
| SCHEMBL8189722 | 0.88 | STAT3 (0.49) | ABCG2GAAMGAMSIMGAM2 | |
| SCHEMBL8189718 | 0.88 | STAT3 (0.49) | ABCG2GAAMGAMSIMGAM2 | |
| SCHEMBL10444656 | 0.87 | NOX1 (0.48) | ABCG2GAATOP1CYCSENPP2 | |
| SCHEMBL29825428 | 0.87 | NOX1 (0.48) | ABCG2GAATOP1CYCSENPP2 | |
| SCHEMBL499168 | 0.87 | ABCG2 (0.49) | ABCG2GAATOP1CYCSENPP2 | |
| SCHEMBL29441514 | 0.87 | ABCG2 (0.49) | ABCG2GAATOP1CYCSENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6087493-A | ENZYME IHIBITORS | REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2000-07-11 | — | — | US | disclosed |
| EP-0988037-A1 | PORPHYRIN COMPOUNDS AS TELOMERASE INHIBITORS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2000-03-29 | — | — | EP | disclosed |
| WO-1998033503-A1 | PORPHYRIN COMPOUNDS AS TELOMERASE INHIBITORS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1998-08-06 | — | — | WO | disclosed |