SCHEMBL499168

SCHEMBL499168

COc1ccc(-c2c3nc(c(-c4ccc(OC)c(OC)c4)c4ccc([nH]4)c(-c4ccc(OC)c(OC)c4)c4nc(c(-c5ccc(OC)c(OC)c5)c5ccc2[nH]5)C=C4)C=C3)cc1OC

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ ABCG2 Q9UNQ0 1/20 0.49
▸ TERT O14746 2/20 0.49
▸ TOP1 P11387 4/20 0.48
▸ CYCS P99999 3/20 0.47
▸ ALOX5 P09917 1/20 0.46
▸ EPHX2 P34913 1/20 0.46
▸ KDM4E B2RXH2 3/20 0.46
▸ ALDH1A1 P00352 3/20 0.46
▸ ENPP2 Q13822 1/20 0.46
▸ GAA P10253 1/20 0.44
▸ MPI P34949 1/20 0.44
▸ GFER P55789 1/20 0.44
▸ APOBEC3G Q9HC16 1/20 0.44
▸ TDP1 Q9NUW8 1/20 0.44
▸ MAPK1 P28482 1/20 0.44
▸ HPGD P15428 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30616085 1.00 ABCG2 (0.49) ABCG2TERTTOP1CYCSALOX5
SCHEMBL29441514 1.00 ABCG2 (0.49) ABCG2TERTTOP1CYCSALOX5
SCHEMBL25278235 0.87 TERT (0.41) ABCG2TERTTOP1CYCSALOX5
SCHEMBL2694939 0.87 NOX1 (0.49) ABCG2TERTTOP1CYCSALDH1A1
SCHEMBL32662346 0.87 NOX1 (0.49) ABCG2TERTTOP1CYCSALDH1A1
SCHEMBL8186763 0.87 ABCG2 (0.49) ABCG2TERTTOP1CYCSKDM4E
Hydrochloric Acid SCHEMBL8187553 0.85 ABCG2 (0.48) ABCG2TERTTOP1CYCSKDM4E
SCHEMBL29825428 0.85 NOX1 (0.48) ABCG2TERTTOP1CYCSALDH1A1
SCHEMBL10444656 0.85 NOX1 (0.48) ABCG2TERTTOP1CYCSALDH1A1
SCHEMBL498533 0.84 TERT (0.49) ABCG2TERTTOP1CYCSKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9867800-B2 Method of quenching singlet and triplet excited states of pigments, such as porphyrin compounds, particularly protoporphyrin IX, with conjugated fused tricyclic compounds have electron withdrawing groups, to reduce generation of reactive oxygen species, particularly singlet oxygen HALLSTAR INNOVATIONS CORP. (US) 2018-01-16 — — US claimed
US-20150164852-A1 METHOD OF QUENCHING SINGLET AND TRIPLET EXCITED STATES OF PIGMENTS, SUCH AS PORPHYRIN COMPOUNDS, PARTICULARLY PROTOPORPHYRIN IX, WITH CONJUGATED FUSED TRICYCLIC COMPOUNDS HAVE ELECTRON WITHDRAWING GROUPS, TO REDUCE GENERATION OF REACTIVE OXYGEN SPECIES, PARTICULARLY SINGLET OXYGEN HALLSTAR INNOVATIONS CORP. (US) 2015-06-18 — — US claimed
WO-2014025370-A1 TRICYCLIC ENERGY QUENCHER COMPOUNDS FOR REDUCING SINGLET OXYGEN GENERATION HALLSTAR INNOVATIONS CORP. (US) 2014-02-13 — — WO claimed
US-12071498-B2 Radically polymerizable compositions Polynt Composites USA, Inc. (US) 2024-08-27 — — US disclosed
CN-113474383-B Free radical polymerizable composition 波林复合材料美国股份有限公司 2023-10-31 — — CN disclosed
US-20230257500-A1 RADICALLY POLYMERIZABLE COMPOSITIONS BNY MELLON CORPORATE TRUSTEE SERVICES LIMITED, AS SECURITY AGENT (GB) 2023-08-17 — — US disclosed
US-11518834-B2 Radically polymerizable compositions Polynt Composites USA, Inc. (US) 2022-12-06 — — US disclosed
EP-3077467-B1 DRIER COMPOSITION AND USE THEREOF PPG EUROPE B V (NL) 2022-11-02 — — EP disclosed
EP-3906265-A1 RADICALLY POLYMERIZABLE COMPOSITIONS Polynt Composites USA Inc. (US) 2021-11-10 — — EP disclosed
CN-113474383-A Radically polymerizable composition 波林复合材料美国股份有限公司 2021-10-01 — — CN disclosed
WO-2020142632-A1 RADICALLY POLYMERIZABLE COMPOSITIONS Polynt Composites USA, Inc. (US) 2020-07-09 — — WO disclosed
EP-1450790-A2 PHOTOSENSITIZING CARBAMATE DERIVATIVES Miravant Pharmaceuticals, Inc. (US) 2004-09-01 — — EP disclosed
US-6609014-B1 Use of PDT to inhibit intimal hyperplasia QLT INC. (CA) 2003-08-19 — — US disclosed
WO-2003028628-A2 PHOTOSENSITIZING CARBAMATE DERIVATIVES MIRAVANT PHARMACEUTICALS, INC. (US) 2003-04-10 — — WO disclosed
EP-0672953-B1 Photosensitive recording material, photosensitive recording medium, and process for producing hologram using this photosensitive recording medium TOPPAN PRINTING CO LTD (JP) 2003-01-15 — — EP disclosed
US-6045953-A COMPRISES A SUBSTRATE, A PHOTOSENSITIVE LAYER FORMED ON THE SUBSTRATE BY COATING A PHOTOSENSITIVE SOLUTION CONTAINING AN ALICYCLIC, SOLVENT SOLUBLE, CATIONIC POLYMERIZABLE EPOXY RESIN AND AN ACRYLATE POLYMER TOPPAN PRINTING CO., LTD. (JP) 2000-04-04 — — US disclosed
EP-0697631-B1 Photosensitive recording material, photosensitive recording medium, and process for producing hologram using this photosensitive recording medium TOPPAN PRINTING CO LTD (JP) 1998-06-10 — — EP disclosed
US-5698345-A CATIONIC POLYMERIZATION OF THERMOSETTING EPOXY OLIGOMER TOPPAN PRINTING CO., LTD. (JP) 1997-12-16 — — US disclosed
EP-0697631-A1 Photosensitive recording material, photosensitive recording medium, and process for producing hologram using this photosensitive recording medium Toppan Printing Co., Ltd. (JP) 1996-02-21 — — EP disclosed
EP-0672953-A2 Photosensitive recording material, photosensitive recording medium, and process for producing hologram using this photosensitive recording medium Toppan Printing Co., Ltd. (JP) 1995-09-20 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150164852-A1 METHOD OF QUENCHING SINGLET AND TRIPLET EXCITED STATES OF PIGMENTS, SUCH AS PORPHYRIN COMPOUNDS, PARTICULARLY PROTOPORPHYRIN IX, WITH CONJUGATED FUSED TRICYCLIC COMPOUNDS HAVE ELECTRON WITHDRAWING GROUPS, TO REDUCE GENERATION OF REACTIVE OXYGEN SPECIES, PARTICULARLY SINGLET OXYGEN NOX3, CBR3, CCR3 ABCG2 2540/4885TERT 1768/4885TOP1 1886/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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