Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 7/20 | 0.59 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.59 |
| ▸ | ECE1 | P42892 | 2/20 | 0.57 |
| ▸ | MME | P08473 | 1/20 | 0.57 |
| ▸ | CTSL | P07711 | 3/20 | 0.56 |
| ▸ | CTSB | P07858 | 2/20 | 0.55 |
| ▸ | CTSS | P25774 | 2/20 | 0.55 |
| ▸ | CTSK | P43235 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | TACR1 | P25103 | 2/20 | 0.53 |
| ▸ | TYR | P14679 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylalanine Amide SCHEMBL8187861 | 0.95 | ITGB3 (0.60) | ITGB3ITGA2BECE1MMECTSL | |
| Phenylalanine SCHEMBL9543648 | 0.94 | ITGB3 (0.53) | ITGB3ITGA2BECE1MMECTSL | |
| SCHEMBL221300 | 0.90 | ECE1 (0.65) | ITGB3ITGA2BECE1MMECTSL | |
| SCHEMBL6118298 | 0.90 | ECE1 (0.65) | ITGB3ITGA2BECE1MMECTSL | |
| SCHEMBL10507966 | 0.90 | ECE1 (0.65) | ITGB3ITGA2BECE1MMECTSL | |
| SCHEMBL1702159 | 0.90 | ECE1 (0.65) | ITGB3ITGA2BECE1MMECTSL | |
| Water SCHEMBL8165165 | 0.89 | CTSL (0.66) | ITGB3ITGA2BECE1MMECTSL | |
| Water SCHEMBL8394834 | 0.89 | CTSL (0.66) | ITGB3ITGA2BECE1MMECTSL | |
| Hydrochloric Acid SCHEMBL11635370 | 0.89 | ECE1 (0.64) | ITGB3ITGA2BECE1MMECTSL | |
| D-Phenylalanine SCHEMBL9445679 | 0.88 | ITGB3 (0.63) | ITGB3ITGA2BECE1MMECTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6025333-A | Treatment of CNS tumors with metalloprotease inhibitors | ERZIEHUNGSDIREKTION OF THE CANTON ZURICH (CH) | 2000-02-15 | — | — | US | claimed |
| EP-0396719-B1 | NEURITE GROWTH REGULATORY FACTORS | ZUERICH ERZIEHUNGSDIREKTION (CH) | 1995-07-05 | — | — | EP | claimed |
| EP-0495204-B1 | Process for the preparation of (6S)- and (6R)-tetrahydrofolic acid | EPROVA AG (CH) | 1995-06-14 | — | — | EP | claimed |
| EP-0495204-A1 | Process for the preparation of (6S)- and (6R)-tetrahydrofolic acid | EPROVA Aktiengesellschaft (CH) | 1992-07-22 | — | — | EP | claimed |
| EP-0396719-A1 | NEURITE GROWTH REGULATORY FACTORS. | 3 G CORP (CH) | 1990-11-14 | — | — | EP | claimed |
| WO-1990005191-A1 | NEURITE GROWTH REGULATORY FACTORS | ERZIEHUNGSDIREKTION OF THE CANTON ZURICH (CH) | 1990-05-17 | — | — | WO | claimed |