SCHEMBL8188154

SCHEMBL8188154

CN1CCC(/C=N/O)CC1

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NCF1 P14598 1/20 0.34
ACHE P22303 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8188157 1.00 NCF1 (0.34) NCF1ACHE
SCHEMBL18828781 0.78 NCF1 (0.36) NCF1ACHE
SCHEMBL22877041 0.78 NCF1 (0.36) NCF1ACHE
SCHEMBL3852773 0.76
SCHEMBL5584088 0.76
SCHEMBL7527085 0.76
SCHEMBL20060226 0.74 NCF1 (0.33) NCF1ACHE
SCHEMBL27463436 0.74 GNAO1 (0.43)
SCHEMBL2600268 0.74 ATM (0.33)
SCHEMBL6783638 0.74 ATM (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2000073287-A1 ISOXAZOLINE CARBOXYLATE DERIVATIVES OF MUTILINE AND THEIR USE AS ANTIBACTERIALS SMITHKLINE BEECHAM PLC (GB) 2000-12-07 WO disclosed