Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | PKLR | P30613 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2781797 | 1.00 | CA12 (0.54) | CA12CA2CA9PKMNPC1 | |
| Fluoride SCHEMBL27399354 | 0.98 | PKM (0.54) | CA12CA2CA9PKMNPC1 | |
| Hydrochloric Acid SCHEMBL27510965 | 0.98 | CA12 (0.53) | CA12CA2CA9PKMNPC1 | |
| SCHEMBL2986914 | 0.88 | PKM (0.66) | PKMNPC1RAB9APKLRALDH1A1 | |
| SCHEMBL30140539 | 0.88 | PKM (0.66) | PKMNPC1RAB9APKLRALDH1A1 | |
| Hydrochloric Acid SCHEMBL27738679 | 0.86 | PKM (0.64) | PKMNPC1RAB9APKLRALDH1A1 | |
| SCHEMBL4747547 | 0.85 | PKM (0.57) | PKMNPC1RAB9APKLRALDH1A1 | |
| SCHEMBL2331607 | 0.83 | SNCA (0.46) | CA12CA2CA9PKMNPC1 | |
| SCHEMBL6061841 | 0.81 | CALM1 (0.55) | PKMCYP3A4ALDH1A1LMNAKDM4E | |
| SCHEMBL8188344 | 0.80 | CA12 (0.54) | CA12CA2CA9PKMNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6066636-A | ALZHEIMER'S DISEASE | SCHERING CORPORATION (US) | 2000-05-23 | — | — | US | disclosed |