Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 5/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.64 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.64 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.64 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.64 |
| ▸ | AR | P10275 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.64 |
| ▸ | ESR1 | P03372 | 1/20 | 0.64 |
| ▸ | TST | Q16762 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7715719 | 1.00 | VDR (0.65) | VDRALDH1A1ALOX15CYP3A4LMNA | |
| SCHEMBL7715741 | 1.00 | VDR (0.65) | VDRALDH1A1ALOX15CYP3A4LMNA | |
| SCHEMBL8179553 | 1.00 | VDR (0.65) | VDRALDH1A1ALOX15CYP3A4LMNA | |
| SCHEMBL8188404 | 1.00 | VDR (0.65) | VDRALDH1A1ALOX15CYP3A4LMNA | |
| SCHEMBL8189720 | 1.00 | VDR (0.65) | VDRALDH1A1ALOX15CYP3A4LMNA | |
| SCHEMBL7715065 | 0.99 | VDR (0.66) | VDRALDH1A1ALOX15CYP3A4LMNA | |
| SCHEMBL7718611 | 0.99 | VDR (0.66) | VDRALDH1A1ALOX15CYP3A4LMNA | |
| SCHEMBL7716712 | 0.97 | VDR (0.67) | VDRALDH1A1ALOX15CYP3A4LMNA | |
| SCHEMBL7710878 | 0.97 | VDR (0.67) | VDRALDH1A1ALOX15CYP3A4LMNA | |
| SCHEMBL7710871 | 0.94 | ALDH1A1 (0.68) | VDRALDH1A1ALOX15CYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832063-B1 | VITAMIN D DERIVATIVES WITH C-25 SUBSTITUENTS, PROCESS FOR THEIR PREPARATION, INTERMEDIATE PRODUCTS AND THEIR USE IN PREPARING MEDICAMENTS | SCHERING AG (DE) | 2000-02-23 | — | — | EP | claimed |
| EP-0832063-B1 | VITAMIN D DERIVATIVES WITH C-25 SUBSTITUENTS, PROCESS FOR THEIR PREPARATION, INTERMEDIATE PRODUCTS AND THEIR USE IN PREPARING MEDICAMENTS | SCHERING AG (DE) | 2000-02-23 | — | — | EP | disclosed |