Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL820841 | 0.87 | KCNH2 (0.35) | — | |
| SCHEMBL185493 | 0.85 | KCNH2 (0.33) | — | |
| SCHEMBL8671436 | 0.84 | KCNH2 (0.46) | — | |
| SCHEMBL1777251 | 0.84 | KCNH2 (0.46) | — | |
| SCHEMBL177368 | 0.81 | — | — | |
| SCHEMBL8466418 | 0.80 | — | — | |
| SCHEMBL5264255 | 0.80 | TDP1 (0.34) | — | |
| SCHEMBL820116 | 0.79 | GABRA1 (0.31) | GABRA1GABRB2 | |
| SCHEMBL820424 | 0.77 | KCNH2 (0.38) | — | |
| SCHEMBL16439955 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3752494-A1 | REACTIONS OF OLEFIN DERIVATIVES IN THE PRESENCE OF METATHESIS CATALYSTS | UMICORE AG & Co. KG (DE) | 2020-12-23 | — | — | EP | claimed |
| WO-2019158485-A1 | REACTIONS OF OLEFIN DERIVATIVES IN THE PRESENCE OF METATHESIS CATALYSTS | UMICORE AG & CO. KG (DE) | 2019-08-22 | — | — | WO | claimed |
| EP-3503999-A1 | SYNTHESIS AND CHARACTERIZATION OF METATHESIS CATALYSTS | UMICORE AG & CO. KG (DE) | 2019-07-03 | — | — | EP | claimed |
| EP-3496855-A1 | METATHESIS CATALYSTS | UMICORE AG & CO. KG (DE) | 2019-06-19 | — | — | EP | claimed |
| WO-2018038928-A1 | SYNTHESIS AND CHARACTERIZATION OF METATHESIS CATALYSTS | MATERIA, INC. (US) | 2018-03-01 | — | — | WO | claimed |
| WO-2018034931-A1 | METATHESIS CATALYSTS | MATERIA, INC. (US) | 2018-02-22 | — | — | WO | claimed |
| US-8426429-B2 | 2-amino-quinazoline derivatives useful as inhibitors of β-secretase (BACE) | JANSSSEN PHARMACEUTICA N.V. (BE) | 2013-04-23 | — | — | US | claimed |
| EP-1776350-B1 | NOVEL 2-AMINO-QUINAZOLINE DERIVATIVES USEFUL AS INHIBITORS OF ß-SECRETASE ( BACE ) | JANSSEN PHARMACEUTICA NV (BE) | 2013-01-23 | — | — | EP | claimed |
| CN-101035770-B | 2-amino-quinazoline derivatives useful as inhibitors of beta-secretase (BACE) | JANSSEN PHARMACEUTICA NV | 2011-02-23 | — | — | CN | claimed |
| CN-101035770-A | Novel 2-amino-quinazoline derivatives useful as inhibitors of beta-secretase (BACE) | JANSSEN PHARMACEUTICA NV (BE) | 2007-09-12 | — | — | CN | claimed |
| EP-1776350-A1 | NOVEL 2-AMINO-QUINAZOLINE DERIVATIVES USEFUL AS INHIBITORS OF ß-SECRETASE ( BACE ) | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-04-25 | — | — | EP | claimed |
| US-20060079686-A1 | Novel 2-amino-quinazoline derivatives useful as inhibitors of beta-secretase (BACE) | JANSSEN PHARMACEUTICA NV (BE) | 2006-04-13 | — | — | US | claimed |
| WO-2006017844-A1 | NOVEL 2-AMINO-QUINAZOLINE DERIVATIVES USEFUL AS INHIBITORS OF β-SECRETASE (BACE) | JANSSEN PHARMACEUTICA, N.V. (BE) | 2006-02-16 | — | — | WO | claimed |
| EP-3583211-B1 | METHOD FOR THE SYNTHESIS OF DNA CONJUGATES BY MICELLAR CATALYSIS | UNIV DORTMUND TECH (DE) | 2024-04-10 | — | — | EP | disclosed |
| EP-3986995-A1 | 1-ALKOXYETHYL-4-ISOBUTYL-BENZENE AS AROMA INGREDIENTS | BASF SE (DE) | 2022-04-27 | — | — | EP | disclosed |
| US-20220002712-A1 | METHOD FOR THE SYNTHESIS OF DNA CONJUGATES BY MICELLAR CATALYSIS | TECHNISCHE UNIVERSITÄT DORTMUND (DE) | 2022-01-06 | — | — | US | disclosed |
| EP-0414511-A1 | Thiadiazole derivatives and herbicide compositions containing the same | Tosoh Corporation (JP) | 1991-02-27 | — | — | EP | disclosed |
| US-4427814-A | DIPHOSPHONITE STABILIZER | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1984-01-24 | — | — | US | disclosed |
| US-4169106-A | Antiarrhythmic N,N'-bis(phenylcarbamoylalkyl)amidines | COOPER LABORATORIES, INC. (US) | 1979-09-25 | — | — | US | disclosed |
| US-4069223-A | ANTIDIARRHEA | G. D. SEARLE & CO. (US) | 1978-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060079686-A1 | Novel 2-amino-quinazoline derivatives useful as inhibitors of beta-secretase (BACE) | BACE2, BACE1, APP | GABRA1 876/4885GABRB2 248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.