⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL177278 | 0.84 | GABRA1 (0.38) | — | |
| SCHEMBL818858 | 0.81 | GABRA1 (0.30) | — | |
| SCHEMBL18706239 | 0.78 | — | — | |
| SCHEMBL7858661 | 0.78 | — | — | |
| SCHEMBL5466454 | 0.78 | — | — | |
| SCHEMBL8465606 | 0.78 | — | — | |
| SCHEMBL2480173 | 0.78 | — | — | |
| SCHEMBL820841 | 0.78 | KCNH2 (0.35) | — | |
| SCHEMBL5178222 | 0.76 | ALDH1A1 (0.39) | — | |
| SCHEMBL28322651 | 0.75 | GABRA1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1826 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115850694-B | Polymeric carbodiimide compound hydrolysis-resistant agent and preparation method and application thereof | 上海朗亿功能材料有限公司 | 2024-06-18 | — | — | CN | claimed |
| US-11958042-B2 | Reactions of olefin derivatives in the presence of metathesis catalysts | UMICORE AG & CO. KG (DE) | 2024-04-16 | — | — | US | claimed |
| CN-112824374-B | Method for preparing chiral amine compound by asymmetric hydrogenation of nickel catalytic imine | 中国科学院大连化学物理研究所 | 2023-06-20 | — | — | CN | claimed |
| US-20230183248-A1 | PYRROLO[1,2-D][1,2,4]TRIAZINE-2-YL-ACETAMIDES AS INHIBITORS OF THE NLRP3 INFLAMMASOME PATHWAY | JANSSEN PHARMACEUTICA NV (BE) | 2023-06-15 | — | — | US | claimed |
| EP-4194092-A1 | SYNTHESIS AND CHARACTERIZATION OF METATHESIS CATALYSTS | Umicore AG & Co. KG (DE) | 2023-06-14 | — | — | EP | claimed |
| CN-115850694-A | Polymeric carbodiimide compound hydrolysis-resistant agent and preparation method and application thereof | 上海朗亿功能材料有限公司 | 2023-03-28 | — | — | CN | claimed |
| EP-4135842-A1 | PYRROLO[1,2-D][1,2,4]TRIAZINE-2-YL-ACETAMIDES AS INHIBITORS OF THE NLRP3 INFLAMMASOME PATHWAY | JANSSEN Pharmaceutica NV (BE) | 2023-02-22 | — | — | EP | claimed |
| CN-115485026-A | Pyrazolo [1,2-D ] [1,2,4] triazin-2-yl-acetamides as NLRP3 inflammatory pathway inhibitors | 詹森药业有限公司 | 2022-12-16 | — | — | CN | claimed |
| EP-3503999-B1 | SYNTHESIS AND CHARACTERIZATION OF METATHESIS CATALYSTS | UMICORE AG & CO KG (DE) | 2022-12-07 | — | — | EP | claimed |
| CN-112625201-B | Carbodiimide polymer, preparation method, intermediate, composition and application | 上海朗亿功能材料有限公司 | 2022-07-19 | — | — | CN | claimed |
| US-4844732-A | PLANT GROWTH REGULATORS | DAICEL CHEMICAL INDUSTRIES LTD. (JP) | 1989-07-04 | — | — | US | claimed |
| EP-0312019-A2 | Condensed heterocyclic compounds, a process for preparing the same and a herbicidal composition thereof | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1989-04-19 | — | — | EP | claimed |
| EP-0302021-A2 | Process for the preparation of optically active secondary aryl amines | UNIVERSITY OF BRITISH COLUMBIA (CA) | 1989-02-01 | — | — | EP | claimed |
| US-4777256-A | PLANT GROWTH REGULATORS, ANTIINFLAMMATORY AGENTS | DAICEL CHEMICAL INDUSTRIES LTD. (JP) | 1988-10-11 | — | — | US | claimed |
| EP-0256982-A2 | Method for the preparation of optically active secondary aryl amines | CIBA-GEIGY AG (CH) | 1988-02-24 | — | — | EP | claimed |
| EP-0161480-B1 | N-IODINE PROPARGYL-CHLOROMETHANESULFONAMIDE | BAYER AG (DE) | 1987-06-03 | — | — | EP | claimed |
| EP-0161480-A1 | N-iodine propargyl-chloromethanesulfonamide | BAYER AG (DE) | 1985-11-21 | — | — | EP | claimed |
| US-4260410-A | Herbicidal and plant-growth-regulating N-haloacetylphenylamino carbonyl oximes | CHEVRON RESEARCH COMPANY (US) | 1981-04-07 | — | — | US | claimed |
| US-4243408-A | PREEMERGENCE AND POSTEMERGENCE; SEEDICIDES | CHEVRON RESEARCH COMPANY (US) | 1981-01-06 | — | — | US | claimed |
| US-4125620-A | HYPOTENSIVE | BOEHRINGER INGELHEIM GMBH (DE) | 1978-11-14 | — | — | US | claimed |