Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARD | Q03181 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.43 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8184303 | 0.92 | MEN1 (0.64) | MEN1KMT2ASMN1; SMN2USP2MAPK1 | |
| SCHEMBL8176766 | 0.89 | ALDH1A1 (0.50) | MEN1KMT2ASMN1; SMN2POLBMAPT | |
| SCHEMBL8184601 | 0.89 | KMT2A (0.49) | MEN1KMT2ASMN1; SMN2USP2MAPK1 | |
| Hydrochloric Acid SCHEMBL8184284 | 0.88 | ALDH1A1 (0.49) | MEN1KMT2ASMN1; SMN2POLBMAPT | |
| SCHEMBL8175290 | 0.88 | KMT2A (0.48) | MEN1KMT2ASMN1; SMN2USP2MAPK1 | |
| SCHEMBL7109075 | 0.87 | MAPT (0.50) | MEN1KMT2ASMN1; SMN2USP2MAPK1 | |
| SCHEMBL8175630 | 0.86 | RAB9A (0.56) | MEN1KMT2ASMN1; SMN2USP2MAPK1 | |
| SCHEMBL8174345 | 0.86 | SMN1; SMN2 (0.47) | MEN1KMT2ASMN1; SMN2USP2MAPK1 | |
| SCHEMBL8185113 | 0.86 | MAPK1 (0.47) | MEN1KMT2ASMN1; SMN2USP2MAPK1 | |
| SCHEMBL8176086 | 0.86 | MAPT (0.45) | MEN1KMT2ASMN1; SMN2USP2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6110934-A | Substituted benzamide derivatives and their use as anticonvulsants | SMITHKLINE BEECHAM P.L.C. (GB) | 2000-08-29 | — | — | US | disclosed |