Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 2/20 | 0.36 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.35 |
| ▸ | TUBB1 | Q9H4B7 | 8/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.35 |
| ▸ | TUBB | P07437 | 2/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8200354 | 0.88 | TRPA1 (0.55) | TRPA1ALDH1A1ELANEKDM4EMAPT | |
| SCHEMBL2771360 | 0.88 | KDM4E (0.46) | TRPA1ALDH1A1ELANEKDM4EMAPT | |
| SCHEMBL24589175 | 0.84 | KDM4E (0.50) | TRPA1ALDH1A1KDM4EMAPTJAK2 | |
| SCHEMBL24589193 | 0.84 | ELANE (0.39) | TRPA1ALDH1A1ELANEKDM4EMAPT | |
| SCHEMBL23558920 | 0.84 | ELANE (0.44) | TRPA1ELANEKDM4EMAPTAPP | |
| SCHEMBL8200395 | 0.82 | TRPA1 (0.49) | TRPA1ALDH1A1ELANEKDM4EMAPT | |
| SCHEMBL26740866 | 0.81 | ALDH1A1 (0.47) | ALDH1A1KDM4EGAA | |
| SCHEMBL1855163 | 0.81 | ALDH1A1 (0.37) | TRPA1ALDH1A1ELANEKDM4EMAPT | |
| SCHEMBL5517515 | 0.80 | GRIN2D (0.43) | ALDH1A1KDM4EMAPTTUBB1GAA | |
| SCHEMBL29030377 | 0.80 | TRPA1 (0.50) | TRPA1ALDH1A1AOX1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6022665-A | BLEND OF SOLVENT, MODIFIED STYRENE POLYMER AND PHOTOACID GENERATOR | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2000-02-08 | — | — | US | disclosed |
| EP-0970079-A1 | FARNESYL TRANSFERASE INHIBITING 1,8-ANNELATED QUINOLINONE DERIVATIVES SUBSTITUTED WITH N- OR C-LINKED IMIDAZOLES | JANSSEN PHARMACEUTICA N.V. (BE) | 2000-01-12 | — | — | EP | disclosed |
| US-5844057-A | Polymers and chemically amplified positive resist compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1998-12-01 | — | — | US | disclosed |
| WO-1998040383-A1 | FARNESYL TRANSFERASE INHIBITING 1,8-ANNELATED QUINOLINONE DERIVATIVES SUBSTITUTED WITH N- OR C-LINKED IMIDAZOLES | JANSSEN PHARMACEUTICA N.V. (BE) | 1998-09-17 | — | — | WO | disclosed |