Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 4/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.38 |
| ▸ | FEN1 | P39748 | 2/20 | 0.38 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.36 |
| ▸ | GRM8 | O00222 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8175336 | 0.77 | GRM1 (0.42) | GRM1BRD4ALOX5APFEN1PGAM1 | |
| SCHEMBL6309814 | 0.71 | DHODH (0.45) | — | |
| SCHEMBL6310856 | 0.70 | DHODH (0.41) | — | |
| SCHEMBL6697503 | 0.70 | BRD4 (0.30) | BRD4 | |
| SCHEMBL6310221 | 0.68 | DHODH (0.38) | — | |
| SCHEMBL6310317 | 0.68 | DHODH (0.38) | — | |
| SCHEMBL8182967 | 0.66 | PSIP1 (0.44) | GRM1BRD4GRM4GRM8GRM5 | |
| SCHEMBL6593157 | 0.65 | TRPV1 (0.33) | — | |
| SCHEMBL10300135 | 0.63 | CYP3A4 (0.41) | GRM1GRM4ESR1ESR2CA1 | |
| SCHEMBL28957696 | 0.63 | GRM1 (0.46) | GRM1GRM4GRM8GRM5GRM7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000010976-A1 | SUBSTITUTED N-ARYL-PHTHALIMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-03-02 | — | — | WO | disclosed |