Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 | P41231 | 8/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PRNP | P04156 | 5/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7491992 | 0.93 | P2RY2 (0.47) | P2RY2KDM4ENPSR1ALDH1A1HPGD | |
| SCHEMBL7494169 | 0.87 | P2RY2 (0.49) | P2RY2ALDH1A1HPGD | |
| SCHEMBL7497294 | 0.70 | KDM4E (0.45) | KDM4ENPSR1ALDH1A1HPGDUSP2 | |
| SCHEMBL7491790 | 0.68 | P2RY2 (0.47) | P2RY2ALDH1A1HPGDUSP2ALOX15 | |
| SCHEMBL7490022 | 0.66 | P2RY2 (0.46) | P2RY2KDM4EALDH1A1HPGDUSP2 | |
| SCHEMBL7592802 | 0.64 | P2RY2 (0.81) | P2RY2HPGD | |
| SCHEMBL7487228 | 0.60 | P2RY2 (0.46) | P2RY2KDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL7488855 | 0.60 | P2RY2 (0.49) | P2RY2ALOX15 | |
| SCHEMBL7488052 | 0.60 | P2RY2 (0.44) | P2RY2GAA | |
| SCHEMBL7598700 | 0.59 | P2RY2 (0.47) | P2RY2KDM4EALDH1A1GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6107297-A | 2,4-Dithi(oxo)-pyrimidin-5-yl compounds bearing a tricyclic substituent useful as P2 purinoceptor antagonists | ASTRA PHARMACEUTICALS LIMITED (GB) | 2000-08-22 | — | — | US | disclosed |