Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLB1 | P16278 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8773040 | 0.87 | GLB1 (0.43) | GLB1 | |
| SCHEMBL7378486 | 0.80 | ALDH1A1 (0.44) | — | |
| SCHEMBL1168296 | 0.78 | — | — | |
| SCHEMBL10963011 | 0.78 | — | — | |
| SCHEMBL29632046 | 0.78 | — | — | |
| SCHEMBL1168294 | 0.78 | — | — | |
| SCHEMBL7066334 | 0.78 | TYMS (0.52) | GLB1 | |
| SCHEMBL3813102 | 0.78 | TYMS (0.52) | GLB1 | |
| SCHEMBL6805481 | 0.78 | TYMS (0.52) | GLB1 | |
| SCHEMBL7333226 | 0.74 | PLAU (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872101-A | Methods of treating neurodegenerative disorders using protease inhibitors | SIBIA NEUROSCIENCES, INC. (US) | 1999-02-16 | — | — | US | claimed |
| US-5863902-A | Methods of treating neurodegenerative disorders using protease inhibitors | SIBIA NEUROSCIENCES, INC. (US) | 1999-01-26 | — | — | US | claimed |
| WO-1996020725-A2 | PEPTIDE, PEPTIDE ANALOG AND AMINO ACID ANALOG PROTEASE INHIBITORS | SIBIA NEUROSCIENCES, INC. (US) | 1996-07-11 | — | — | WO | claimed |
| US-6017887-A | Peptide, peptide analog and amino acid analog protease inhibitors | SIBIA NEUROSCIENCES, INC. (US) | 2000-01-25 | — | — | US | disclosed |
| US-5969100-A | Peptide, peptide analog and amino acid analog protease inhibitors | SIBIA NEUROSCIENCES, INC. (US) | 1999-10-19 | — | — | US | disclosed |
| US-5872101-A | Methods of treating neurodegenerative disorders using protease inhibitors | SIBIA NEUROSCIENCES, INC. (US) | 1999-02-16 | — | — | US | disclosed |
| US-5863902-A | Methods of treating neurodegenerative disorders using protease inhibitors | SIBIA NEUROSCIENCES, INC. (US) | 1999-01-26 | — | — | US | disclosed |
| WO-1996020725-A2 | PEPTIDE, PEPTIDE ANALOG AND AMINO ACID ANALOG PROTEASE INHIBITORS | SIBIA NEUROSCIENCES, INC. (US) | 1996-07-11 | — | — | WO | disclosed |