Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 7/20 | 0.67 |
| ▸ | FAAH | O00519 | 4/20 | 0.67 |
| ▸ | GSK3A | P49840 | 5/20 | 0.56 |
| ▸ | GSK3B | P49841 | 5/20 | 0.56 |
| ▸ | ELANE | P08246 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | CTSG | P08311 | 1/20 | 0.42 |
| ▸ | CMA1 | P23946 | 1/20 | 0.42 |
| ▸ | CTRC | Q99895 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | RGS4 | P49798 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL598742 | 0.81 | MGLL (0.64) | MGLLFAAHGSK3AGSK3BELANE | |
| SCHEMBL1908629 | 0.81 | MGLL (0.64) | MGLLFAAHGSK3AGSK3BELANE | |
| SCHEMBL22320218 | 0.81 | MGLL (1.00) | MGLLFAAHGSK3AGSK3BELANE | |
| SCHEMBL24478757 | 0.78 | MGLL (0.61) | MGLLFAAHGSK3AGSK3BELANE | |
| SCHEMBL24478758 | 0.74 | MGLL (0.56) | MGLLFAAHGSK3AGSK3BELANE | |
| SCHEMBL207740 | 0.74 | MGLL (1.00) | MGLLFAAHGSK3AGSK3BELANE | |
| SCHEMBL25435490 | 0.74 | MGLL (1.00) | MGLLFAAHGSK3AGSK3BELANE | |
| SCHEMBL21215698 | 0.74 | MGLL (0.86) | MGLLFAAHGSK3AGSK3BELANE | |
| SCHEMBL24478879 | 0.69 | MGLL (0.49) | MGLLFAAHGSK3AGSK3BPTGS1 | |
| SCHEMBL28874121 | 0.68 | MGLL (0.78) | MGLLFAAHGSK3AGSK3BELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008083967-A2 | PROCESS FOR PREPARING 5-BIPHENYL-4-AMINO-2-METHYL PENTANOIC ACID | NOVARTIS AG (CH) | 2008-07-17 | — | — | WO | disclosed |