SCHEMBL24478758

SCHEMBL24478758

CCCC/C=C1\C=CC(=O)N1Cc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ MGLL Q99685 9/20 0.56
▸ GSK3A P49840 4/20 0.56
▸ GSK3B P49841 4/20 0.56
▸ FAAH O00519 4/20 0.46
▸ ELANE P08246 3/20 0.42
▸ F2 P00734 1/20 0.42
▸ PLG P00747 1/20 0.42
▸ CTSG P08311 1/20 0.42
▸ CMA1 P23946 1/20 0.42
▸ CTRC Q99895 1/20 0.42
▸ MEN1 O00255 2/20 0.40
▸ KMT2A Q03164 2/20 0.40
▸ ALDH1A1 P00352 2/20 0.40
▸ NPSR1 Q6W5P4 1/20 0.40
▸ KDM4E B2RXH2 1/20 0.39
▸ HPGD P15428 1/20 0.39
▸ RECQL P46063 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24478757 0.78 MGLL (0.61) MGLLGSK3AGSK3BFAAHELANE
SCHEMBL24478879 0.75 MGLL (0.49) MGLLGSK3AGSK3BFAAHMEN1
SCHEMBL28256798 0.75 MGLL (0.69) MGLLGSK3AGSK3BFAAHMEN1
SCHEMBL8189917 0.74 MGLL (0.67) MGLLGSK3AGSK3BFAAHELANE
SCHEMBL207740 0.74 MGLL (1.00) MGLLGSK3AGSK3BFAAHELANE
SCHEMBL25435490 0.74 MGLL (1.00) MGLLGSK3AGSK3BFAAHELANE
SCHEMBL598742 0.70 MGLL (0.64) MGLLGSK3AGSK3BFAAHELANE
SCHEMBL1908629 0.70 MGLL (0.64) MGLLGSK3AGSK3BFAAHELANE
SCHEMBL28923787 0.69 MGLL (0.57) MGLLGSK3AGSK3BFAAHELANE
SCHEMBL28874121 0.68 MGLL (0.78) MGLLGSK3AGSK3BFAAHELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12479799-B2 Bioconjugation reagent and methods UNIVERSITEIT GENT (BE) 2025-11-25 — — US disclosed
US-20220169604-A1 BIOCONJUGATION REAGENT AND METHODS UNIVERSITEIT GENT (BE) 2022-06-02 — — US disclosed
US-9593108-B2 Compounds and methods for antiviral treatment PTC THERAPEUTICS, INC. (US) 2017-03-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220169604-A1 BIOCONJUGATION REAGENT AND METHODS PIGS, MACF1, PTMA MGLL 1426/4885GSK3A 1727/4885GSK3B 1646/4885
US-12479799-B2 Bioconjugation reagent and methods PIGS, MACF1, PTMA MGLL 1426/4885GSK3A 1727/4885GSK3B 1646/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback