Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | LPL | P06858 | 2/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.35 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.35 |
| ▸ | TRPV2 | Q9Y5S1 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8367478 | 0.89 | CNR1 (0.40) | CNR1CNR2LPLLIPGKIF11 | |
| SCHEMBL2663547 | 0.85 | PARP1 (0.40) | KIF11PDK2ALOX15ALOX12TRPA1 | |
| SCHEMBL9589157 | 0.83 | ALOX15 (0.50) | CNR1CNR2LPLLIPGKIF11 | |
| SCHEMBL8119783 | 0.81 | TAAR1 (0.53) | KIF11ALOX15TAAR1MAPTGFER | |
| SCHEMBL10911819 | 0.81 | CNR1 (0.40) | CNR1CNR2LPLLIPGPDK2 | |
| SCHEMBL27044834 | 0.79 | SKP2 (0.42) | CNR2LPLLIPGNPC1RAB9A | |
| SCHEMBL6600310 | 0.79 | CETP (0.39) | KIF11ALOX15ALOX12TRPA1CETP | |
| SCHEMBL26696493 | 0.77 | KIF11 (0.37) | KIF11ALOX15ALOX12CETP | |
| SCHEMBL10769004 | 0.77 | KIF11 (0.41) | KIF11ALOX15ALOX12CETPTAAR1 | |
| SCHEMBL5752488 | 0.77 | CETP (0.38) | CNR2KIF11PDK2ALOX15ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008063668-A1 | HETEROBICYCLIC METALLOPROTEASE INHIBITORS | ALANTOS PHARMACEUTICALS HOLDING, INC. (US) | 2008-05-29 | — | — | WO | disclosed |