Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MGMT | P16455 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.35 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.35 |
| ▸ | SENP5 | Q96HI0 | 1/20 | 0.35 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.35 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5659575 | 0.70 | CYP19A1 (0.42) | CYP19A1LMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL8194414 | 0.66 | CYP19A1 (0.41) | CYP19A1LMNAHTTSMN1; SMN2NPC1 | |
| SCHEMBL29097580 | 0.65 | NPC1 (0.52) | LMNAHTTSMN1; SMN2NPC1MAPT | |
| SCHEMBL9409815 | 0.64 | ALOX5 (0.53) | LMNAHTTSMN1; SMN2NPC1MAPT | |
| SCHEMBL26022674 | 0.64 | MAOB (0.47) | CYP19A1LMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL31190951 | 0.64 | MAOB (0.47) | CYP19A1LMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL31632401 | 0.64 | MAOB (0.47) | CYP19A1LMNASMN1; SMN2MAPTHPGD | |
| SCHEMBL5579908 | 0.64 | TSPO (0.43) | CYP19A1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL9007594 | 0.64 | MGMT (0.50) | CYP19A1LMNAHTTSMN1; SMN2NPC1 | |
| SCHEMBL8566311 | 0.64 | MGMT (0.61) | LMNAHTTMAPTHPGDMGMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6060608-A | ANTITUMOR AGENTS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2000-05-09 | — | — | US | disclosed |