Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | AHR | P35869 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11393581 | 0.81 | POLB (0.31) | — | |
| SCHEMBL11397144 | 0.81 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3AHR | |
| SCHEMBL5275317 | 0.78 | S1PR1 (0.41) | S1PR1 | |
| SCHEMBL1506620 | 0.77 | S1PR1 (0.46) | S1PR1ABL1 | |
| SCHEMBL4774742 | 0.76 | ALDH1A1 (0.47) | — | |
| SCHEMBL2867341 | 0.76 | PARP1 (0.37) | — | |
| SCHEMBL10907121 | 0.76 | ALOX15 (0.45) | — | |
| SCHEMBL5435393 | 0.76 | SLC6A2 (0.37) | SLC6A2SLC6A4SLC6A3AHR | |
| SCHEMBL7932053 | 0.76 | ALDH1A1 (0.42) | SLC6A2SLC6A4 | |
| SCHEMBL21821087 | 0.75 | S1PR1 (0.41) | SLC6A2SLC6A4S1PR1ABL1SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115403584-B | 2-thio-2, 3-dihydropyrimidine-4-one derivatives, pharmaceutical compositions, preparation methods and applications thereof | 长春金赛药业有限责任公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-115403584-A | 2-thio-2, 3-dihydropyrimidine-4-one derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-11-29 | — | — | CN | disclosed |
| US-6162918-A | Xanthene and acridine derivatives | HOFFMANN-LA ROCHE INC. (US) | 2000-12-19 | — | — | US | disclosed |
| US-5969139-A | INHIBITORS OF HERPES SIMPLEX VIRUS THYMIDINE KINASE | HOFFMANN-LA ROCHE INC. (US) | 1999-10-19 | — | — | US | disclosed |
| EP-0823426-A1 | Xanthene and acridine derivatives and their use | F. HOFFMANN-LA ROCHE AG (CH) | 1998-02-11 | — | — | EP | disclosed |