Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 4/20 | 0.60 |
| ▸ | MAOB | P27338 | 1/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.56 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.56 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.55 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.54 |
| ▸ | HPD | P32754 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | FAAH | O00519 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | NAAA | Q02083 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.48 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22717033 | 0.81 | NR4A2 (0.70) | NR4A2MAOBPTPN1KDM2BSMPD1 | |
| SCHEMBL16111895 | 0.81 | SMPD1 (0.63) | NR4A2MAOBSMPD1SPHK2 | |
| SCHEMBL8414533 | 0.80 | KDM4E (0.57) | SMPD1NR1H4MEN1KMT2A | |
| SCHEMBL4882317 | 0.80 | F10 (0.57) | NR1H4MEN1KMT2ASPHK2 | |
| SCHEMBL8189375 | 0.80 | NR4A2 (0.77) | NR4A2MAOBPTPN1SMPD1SRD5A2 | |
| SCHEMBL8411917 | 0.78 | POLB (0.62) | NR4A2MAOBPTPN1KDM2BHPD | |
| SCHEMBL3456937 | 0.77 | MAOB (0.57) | NR4A2MAOBPTPN1KDM2BSMPD1 | |
| SCHEMBL3460346 | 0.77 | SMPD1 (0.62) | NR4A2MAOBPTPN1SMPD1FAAH | |
| SCHEMBL8193954 | 0.77 | NR4A2 (0.72) | NR4A2MAOBPTPN1SMPD1SRD5A2 | |
| SCHEMBL339009 | 0.76 | NR4A2 (1.00) | NR4A2MAOBPTPN1SMPD1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070027199-A1 | Cycloalkyl amino-hydantoin compounds and use thereof for beta-secretase modulation | WYETH (US) | 2007-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070027199-A1 | Cycloalkyl amino-hydantoin compounds and use thereof for beta-secretase modulation | BACE1, BACE2, APP | NR4A2 2248/4885MAOB 512/4885PTPN1 4636/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.