Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.56 |
| ▸ | FAAH | O00519 | 1/20 | 0.56 |
| ▸ | CNR2 | P34972 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | GPR132 | Q9UNW8 | 2/20 | 0.56 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.53 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.53 |
| ▸ | GUSB | P08236 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8985626 | 0.90 | SMPD1 (0.60) | SMPD1MEN1KMT2ANR4A2HDAC6 | |
| SCHEMBL5968109 | 0.83 | SGMS2 (0.55) | MEN1KMT2APOLBMAOBNPC1 | |
| SCHEMBL2858452 | 0.82 | MEN1 (0.51) | MEN1KMT2ACNR2HDAC6POLB | |
| SCHEMBL13430713 | 0.81 | BRD4 (0.56) | MEN1KMT2AHDAC6POLB | |
| SCHEMBL10722330 | 0.81 | MEN1 (0.81) | MEN1KMT2AHDAC6POLBNPC1 | |
| SCHEMBL1123392 | 0.80 | GPR132 (0.78) | SMPD1GPR132 | |
| SCHEMBL25123079 | 0.79 | SMN1; SMN2 (0.76) | MEN1KMT2AHDAC6POLBNPC1 | |
| SCHEMBL4522241 | 0.79 | SMN1; SMN2 (0.76) | MEN1KMT2AHDAC6POLBNPC1 | |
| SCHEMBL8395225 | 0.79 | SMN1; SMN2 (0.76) | MEN1KMT2AHDAC6POLBNPC1 | |
| SCHEMBL4195142 | 0.79 | MEN1 (0.66) | MEN1KMT2AHDAC6POLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2239012-A2 | Pharmaceutical use of substituted amides | High Point Pharmaceuticals, LLC (US) | 2010-10-13 | — | — | EP | claimed |