Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 6/20 | 0.37 |
| ▸ | CA1 | P00915 | 6/20 | 0.37 |
| ▸ | CA2 | P00918 | 6/20 | 0.37 |
| ▸ | CA7 | P43166 | 6/20 | 0.37 |
| ▸ | CA9 | Q16790 | 6/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL819220 | 0.87 | ALDH1A1 (0.42) | TSHRESR1CYP3A4KDM4EMAPT | |
| SCHEMBL817434 | 0.84 | TSHR (0.47) | TSHRESR1CYP3A4KDM4EMAPT | |
| SCHEMBL817550 | 0.84 | TSHR (0.45) | TSHRESR1CYP1A2CYP3A4MAPT | |
| SCHEMBL31196992 | 0.83 | TSHR (0.48) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL818075 | 0.83 | ALDH1A1 (0.49) | TSHRESR1CYP3A4KDM4EMAPT | |
| SCHEMBL819445 | 0.82 | ALDH1A1 (0.44) | TSHRMEN1KMT2AKDM4EMAPT | |
| SCHEMBL817805 | 0.80 | CRHBP (0.44) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL5153493 | 0.77 | TSHR (0.40) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL817190 | 0.76 | CA12 (0.37) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL11605886 | 0.76 | TSHR (0.39) | TSHRCA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236908-B2 | Components and catalysts for the polymerization of olefins | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-08-07 | — | — | US | disclosed |
| US-20110269927-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-11-03 | — | — | US | disclosed |