Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 8/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.62 |
| ▸ | TSHR | P16473 | 6/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.62 |
| ▸ | TP53 | P04637 | 4/20 | 0.62 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.62 |
| ▸ | GLA | P06280 | 2/20 | 0.62 |
| ▸ | KDM1A | O60341 | 2/20 | 0.62 |
| ▸ | CASP1 | P29466 | 2/20 | 0.62 |
| ▸ | CASP7 | P55210 | 2/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.62 |
| ▸ | TOP2A | P11388 | 2/20 | 0.62 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.62 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.62 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.62 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.62 |
| ▸ | TOP1 | P11387 | 1/20 | 0.62 |
| ▸ | DRD2 | P14416 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10123701 | 0.86 | LMNA (0.60) | CYP1A2CYP2D6CYP3A4TSHRCYP2C9 | |
| SCHEMBL10108656 | 0.86 | CYP1A2 (0.62) | CYP1A2CYP2D6CYP3A4TSHRCYP2C9 | |
| SCHEMBL8738964 | 0.78 | NR3C2 (0.66) | CYP1A2CYP2D6CYP3A4TSHRCYP2C9 | |
| Amsacrine SCHEMBL28336991 | 0.77 | TOP2B (1.00) | CYP1A2CYP2D6CYP3A4TSHRCYP2C9 | |
| Amsacrine SCHEMBL6256280 | 0.77 | TOP2B (1.00) | CYP1A2CYP2D6CYP3A4TSHRCYP2C9 | |
| Amsacrine SCHEMBL29360354 | 0.77 | TOP2B (1.00) | CYP1A2CYP2D6CYP3A4TSHRCYP2C9 | |
| Amsacrine SCHEMBL4047 | 0.77 | TOP2B (1.00) | CYP1A2CYP2D6CYP3A4TSHRCYP2C9 | |
| Amsacrine SCHEMBL29350869 | 0.77 | TOP2B (1.00) | CYP1A2CYP2D6CYP3A4TSHRCYP2C9 | |
| Amsacrine SCHEMBL1320825 | 0.76 | KMT2A (1.00) | CYP1A2CYP2D6CYP3A4TSHRCYP2C9 | |
| Amsacrine SCHEMBL31316257 | 0.76 | KMT2A (1.00) | CYP1A2CYP2D6CYP3A4TSHRCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008097546-A2 | COMPOUNDS THAT INHIBIT CHOLINESTERASE | COLUCID PHARMACEUTICALS, INC. (US) | 2008-08-14 | — | — | WO | disclosed |