Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | GJB2 | P29033 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GJA1 | P17302 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10431960 | 0.78 | GJB2 (0.42) | SLC6A2PDE4DGJB2 | |
| SCHEMBL6763188 | 0.76 | IDO1 (0.41) | SLC6A2PDE4DKDM4EIDO1KMT2A | |
| SCHEMBL8193121 | 0.76 | IDO1 (0.41) | SLC6A2PDE4DKDM4EIDO1KMT2A | |
| SCHEMBL9146062 | 0.76 | IDO1 (0.41) | SLC6A2PDE4DKDM4EIDO1KMT2A | |
| SCHEMBL8192755 | 0.76 | IDO1 (0.41) | SLC6A2PDE4DKDM4EIDO1KMT2A | |
| SCHEMBL8193352 | 0.76 | IDO1 (0.41) | SLC6A2PDE4DKDM4EIDO1KMT2A | |
| SCHEMBL4953874 | 0.73 | — | — | |
| SCHEMBL22992300 | 0.71 | PDE4D (0.48) | SLC6A2PDE4DGJB2 | |
| SCHEMBL9843718 | 0.71 | PDE4D (0.48) | SLC6A2PDE4DGJB2 | |
| SCHEMBL9844144 | 0.71 | PDE4D (0.48) | SLC6A2PDE4DGJB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6121431-A | VIRICIDES AGAINST HUMAN IMMUNODEFICIENCY VIRUS AND HEPATITIS B VIRUS | MEDIVIR AB (SE) | 2000-09-19 | — | — | US | disclosed |
| US-5952500-A | VIRICIDES CAN BE USED IN THERAPEUTIC AND PROPHYLACTIC TREATMENT OF THE ACQUIRED IMMUNE DEFICIENCY SYNDROME (AIDS), INFECTIONS OF HUMAN IMMUNE DEFICIENCY VIRUSES, HEPATITIS B VIRUS, HERPES VIRUSES AND CANCER | MEDIVIR AB (SE) | 1999-09-14 | — | — | US | disclosed |
| US-5747473-A | L-nucleoside analogues and pharmaceutical compositions | MEDIVIR AB (SE) | 1998-05-05 | — | — | US | disclosed |
| US-5473063-A | Reacting 2,3-epoxy-butanediol/1,4-/(having protected hydroxyl groups) with an alpha allylic nucleophile yields 2-hydroxy-3-allyl-1,4-butanediol, then oxidatively cleaving the double bond, cyclization, halogenation, acetylation or oxyalkylation | MEDIVIR AB (SE) | 1995-12-05 | — | — | US | disclosed |
| WO-1992006102-A1 | NUCLEOSIDE DERIVATIVES | MEDIVIR AB (SE) | 1992-04-16 | — | — | WO | disclosed |