Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 2/20 | 1.00 |
| ▸ | GRIA1 | P42261 | 1/20 | 1.00 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Gyki-53655 SCHEMBL351325 | 1.00 | GRIA2 (1.00) | GRIA2GRIA1MEN1KMT2ACYP1A2 | |
| Gyki-53655 SCHEMBL30259941 | 1.00 | GRIA2 (1.00) | GRIA2GRIA1MEN1KMT2ACYP1A2 | |
| Gyki-53655 SCHEMBL25271920 | 0.99 | GRIA2 (0.98) | GRIA2GRIA1MEN1KMT2ACYP1A2 | |
| Gyki-53655 SCHEMBL30389810 | 0.99 | GRIA2 (0.98) | GRIA2GRIA1MEN1KMT2ACYP1A2 | |
| SCHEMBL5881321 | 0.89 | GRIA2 (0.81) | GRIA2GRIA1MEN1KMT2ACYP1A2 | |
| SCHEMBL30259935 | 0.89 | GRIA2 (0.81) | GRIA2GRIA1MEN1KMT2ACYP1A2 | |
| Talampanel SCHEMBL118011 | 0.89 | GRIA2 (0.80) | GRIA2GRIA1MEN1KMT2ACYP1A2 | |
| SCHEMBL118013 | 0.89 | GRIA2 (0.80) | GRIA2GRIA1MEN1KMT2ACYP1A2 | |
| Talampanel SCHEMBL118012 | 0.89 | GRIA2 (0.80) | GRIA2GRIA1MEN1KMT2ACYP1A2 | |
| Talampanel SCHEMBL30272868 | 0.89 | GRIA2 (0.80) | GRIA2GRIA1MEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260071276-A1 | GPCR LATROPHILIN-3 AS BIOMARKER FOR DETECTING INCREASED RISK FOR MILD BRAIN INJURY AND METHODS OF USE THEREOF FOR DIAGNOSIS AND TREATMENT OF THE SAME | THE CHILDREN'S HOSPITAL OF PHILADELPHIA (US) | 2026-03-12 | — | — | US | disclosed |
| US-6160133-A | Synthesis of (S)-α-methyl-1,3-benzodioxole-5-ethanol and derivatives | ELI LILLY AND COMPANY (US) | 2000-12-12 | — | — | US | disclosed |
| US-5986114-A | MUSCLE RELAXANTS, NERVOUS SYSTEM DISORDERS OR ANTICONVULSANTS | ELI LILLY AND COMPANY (US) | 1999-11-16 | — | — | US | disclosed |
| US-5665878-A | Stereoselective process for producing dihydro-2,3-benzodiazepine derivatives | ELI LILLY AND COMPANY (US) | 1997-09-09 | — | — | US | disclosed |
| EP-0699677-A1 | Stereoselective process for producing dihydro-2,3-benzodiazepine derivatives | ELI LILLY AND COMPANY (US) | 1996-03-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260071276-A1 | GPCR LATROPHILIN-3 AS BIOMARKER FOR DETECTING INCREASED RISK FOR MILD BRAIN INJURY AND METHODS OF USE THEREOF FOR DIAGNOSIS AND TREATMENT OF THE SAME | GPR3, OPRL1, ADGRF1 | GRIA2 377/4885GRIA1 539/4885MEN1 3333/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.