Biphenyl

Biphenyl

SCHEMBL819335

C1=CCC([Zr]C2=CC=CC2)=C1.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
MAPK1 P28482 1/20 0.36
MAPT P10636 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
SLC22A2 O15244 1/20 0.33
SLC22A1 O15245 1/20 0.33
SLC22A3 O75751 1/20 0.33
SLC6A4 P31645 1/20 0.33
CYP1A2 P05177 2/20 0.31
CYP3A4 P08684 1/20 0.31
TAAR1 Q96RJ0 1/20 0.31
HSD17B10 Q99714 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
NOTUM Q6P988 1/20 0.31
MMP3 P08254 1/20 0.31
BCL2L1 Q07817 1/20 0.31
CYP1A1 P04798 1/20 0.30
CYP1B1 Q16678 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL28489637 0.89
Toluene SCHEMBL28481276 0.85 LMNA (0.46) ALDH1A1MAPK1
Bromobenzene SCHEMBL7600505 0.85 ALDH1A1 (0.46) ALDH1A1MAPK1TDP1
Toluene SCHEMBL7669666 0.83 LMNA (0.44) ALDH1A1MAPK1
Iodobenzene SCHEMBL6914272 0.83
Chlorobenzene SCHEMBL819465 0.83 TSHR (0.44) CYP1A2
SCHEMBL648363 0.83
SCHEMBL61348 0.83
SCHEMBL10381944 0.83
SCHEMBL27260142 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 598 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6982236-B2 Process to polymerize olefins UNIVATION TECHNOLOGIES, LLC (US) 2006-01-03 US claimed
US-6897273-B2 Catalyst composition, method of polymerization and polymer therefrom UNIVATION TECHNOLOGIES, LLC (US) 2005-05-24 US claimed
EP-1392743-A2 CATALYST COMPOSITION, METHOD OF POLYMERIZATION AND POLYMER THEREFROM Univation Technologies LLC (US) 2004-03-03 EP claimed
US-20040039138-A1 Catalyst preparation method WENZEL TIMOTHY T (US) 2004-02-26 US claimed
US-6656866-B2 Metallocene and non-metallocene, homogeneous catalysts, particularly for use in the economical gas and slurry phase processes; spray dried olefin polymerization catalysts UNIVATION TECHNOLOGIES, LLC 2003-12-02 US claimed
US-20030207762-A9 CATALYST PREPARATION METHOD UNIVATION TECHNOLOGIES, LLC 2003-11-06 US claimed
EP-1358216-A2 START-UP PROCEDURE FOR MULTIPLE CATALYST POLYMERIZATION SYSTEMS Univation Technologies LLC (US) 2003-11-05 EP claimed
US-6620894-B2 Calibration; using coordination catalyst UNIVATION TECHNOLOGIES, LLC 2003-09-16 US claimed
US-20020132937-A1 Start-up procedure for multiple catalyst polymerization systems UNIVATION TECHNOLOGIES, LLC 2002-09-19 US claimed
US-20020119890-A1 Catalyst preparation method WENZEL TIMOTHY T (US) 2002-08-29 US claimed
WO-1990005149-A1 METHOD FOR UTILIZING TRIETHYLALUMINUM TO PREPARE AN ALUMOXANE SUPPORT FOR AN ACTIVE METALLOCENE CATALYST EXXON CHEMICAL PATENTS INC. (US) 1990-05-17 WO claimed
EP-0368644-A1 Method for utilizing triethylaluminum to prepare an alumoxane support for an active metallocene catalyst EXXON CHEMICAL PATENTS INC. (US) 1990-05-16 EP claimed
US-4925821-A SILICA GEL CATALYST SUPPORT EXXON CHEMICAL PATENTS INC. (US) 1990-05-15 US claimed
EP-0367503-A1 Method for utilizing triethylaluminum to prepare an alumoxane support for an active metallocene catalyst EXXON CHEMICAL PATENTS INC. (US) 1990-05-09 EP claimed
EP-0367597-A1 Method for preparing polyethylene wax by gas phase polymerization EXXON CHEMICAL PATENTS INC. (US) 1990-05-09 EP claimed
WO-1990003403-A1 A SUPPORTED METALLOCENE-ALUMOXANE CATLYST FOR HIGH PRESSURE POLYMERISATION OF OLEFINS AND A METHOD OF PREPARING AND USING THE SAME EXXON CHEMICAL PATENTS INC. (US) 1990-04-05 WO claimed
EP-0361866-A1 A supperted metallocene-allumoxane catalyst for high pressure polymerization of olefins and a method of preparing and using the same EXXON CHEMICAL PATENTS INC. (US) 1990-04-04 EP claimed
US-4914253-A USING A SUPPORTED GROUP 4 OR 5 METALLOCENE-ALUMOXANE CATALYST; MOLECULAR WEIGHT CONTROL WITH HYDROGEN EXXON CHEMICAL PATENTS INC. (US) 1990-04-03 US claimed
US-4912075-A Mixing silic gel with trialkyl aluminum and metallocene EXXON CHEMICAL PATENTS INC. (US) 1990-03-27 US claimed
EP-0323716-A1 Method for preparing a supported metallocene-alumoxane catalyst for gas phase polymerization EXXON CHEMICAL PATENTS INC. (US) 1989-07-12 EP claimed