20-Hydroxyecdysone

20-Hydroxyecdysone

SCHEMBL8193574

CC(C)(O)CCC(O)[C@](C)(O)[C@H]1CCC2(O)C3=CC(=O)C4CC(O)C(O)C[C@]4(C)[C@H]3CC[C@]12C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.71
▸ KMT2A Q03164 1/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
20-Hydroxyecdysone SCHEMBL20033388 1.00 MEN1 (0.71) MEN1KMT2A
20-Hydroxyecdysone SCHEMBL9481370 1.00 MEN1 (0.71) MEN1KMT2A
20-Hydroxyecdysone SCHEMBL6243068 1.00 MEN1 (0.71) MEN1KMT2A
20-Hydroxyecdysone SCHEMBL8193572 1.00 MEN1 (0.71) MEN1KMT2A
20-Hydroxyecdysone SCHEMBL990951 1.00 MEN1 (0.71) MEN1KMT2A
20-Hydroxyecdysone SCHEMBL22087 1.00 MEN1 (0.71) MEN1KMT2A
20-Hydroxyecdysone SCHEMBL8861138 1.00 MEN1 (0.71) MEN1KMT2A
20-Hydroxyecdysone SCHEMBL17580332 1.00 MEN1 (0.71) MEN1KMT2A
20-Hydroxyecdysone SCHEMBL8861142 1.00 MEN1 (0.71) MEN1KMT2A
20-Hydroxyecdysone SCHEMBL3043993 1.00 MEN1 (0.71) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0684826-B1 ECDYSONES USED TO IMPROVE PRODUCTIVITY OF RUMINANTS COMMW SCIENT IND RES ORG (AU) 2000-10-18 — — EP disclosed
EP-0592535-B1 STABLE DOUBLE EMULSIONS CONTAINING FINELY-DIVIDED PARTICLES JOHNSON & SON INC S C (US) 1997-08-27 — — EP disclosed
EP-0592535-A4 STABLE DOUBLE EMULSIONS CONTAINING FINELY-DIVIDED PARTICLES JOHNSON & SON INC S C (US) 1994-07-06 — — EP disclosed
EP-0592535-A1 STABLE DOUBLE EMULSIONS CONTAINING FINELY-DIVIDED PARTICLES. JOHNSON & SON INC S C (US) 1994-04-20 — — EP disclosed
US-5178871-A Emulsification of hydrocarbon oil and water mixture S. C. JOHNSON & SON, INC. (US) 1993-01-12 — — US disclosed
WO-1993000007-A1 STABLE DOUBLE EMULSIONS CONTAINING FINELY-DIVIDED PARTICLES S.C. JOHNSON & SON, INC. (US) 1993-01-07 — — WO disclosed
EP-0498798-A4 COLLAPSIBLE ARTHROPODICIDALLY-ACTIVE FOAM MATRIX AND METHOD OF MANUFACTURE — 1992-10-07 — — EP disclosed
EP-0478578-A4 WATER-SOLUBLE STABLE ARTHROPODICIDALLY-ACTIVE FOAM MATRIX AND METHOD OF MANUFACTURE — 1992-10-07 — — EP disclosed
EP-0498798-A1 COLLAPSIBLE ARTHROPODICIDALLY-ACTIVE FOAM MATRIX AND METHOD OF MANUFACTURE S.C. JOHNSON & SON, INC. (US) 1992-08-19 — — EP disclosed
US-5116618-A Water-soluble arthropodicidally-active foam matrix and method of manufacture S. C. JOHNSON & SON, INC. (US) 1992-05-26 — — US disclosed
US-5104658-A Aqueous lower alkanol solvent, emusifier and toxicant; water soluble S. C. JOHNSON & SON, INC. (US) 1992-04-14 — — US disclosed
EP-0478578-A1 WATER-SOLUBLE STABLE ARTHROPODICIDALLY-ACTIVE FOAM MATRIX AND METHOD OF MANUFACTURE S.C. JOHNSON & SON, INC. (US) 1992-04-08 — — EP disclosed
US-5094853-A Edible, for cockroaches S. C. JOHNSON & SON, INC. (US) 1992-03-10 — — US disclosed
WO-1991006214-A1 COLLAPSIBLE ARTHROPODICIDALLY-ACTIVE FOAM MATRIX AND METHOD OF MANUFACTURE S.C. JOHNSON & SON, INC. (US) 1991-05-16 — — WO disclosed
WO-1990012502-A1 WATER-SOLUBLE STABLE ARTHROPODICIDALLY-ACTIVE FOAM MATRIX AND METHOD OF MANUFACTURE S.C. JOHNSON & SON, INC. (US) 1990-11-01 — — WO disclosed
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