20-Hydroxyecdysone

20-Hydroxyecdysone

SCHEMBL17580332

CC(C)(O)CC[C@@H](O)C(C)(O)[C@H]1CC[C@@]2(O)C3=CC(=O)[C@@H]4C[C@@H](O)[C@@H](O)C[C@]4(C)C3CC[C@]12C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.71
▸ KMT2A Q03164 1/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
20-Hydroxyecdysone SCHEMBL20033388 1.00 MEN1 (0.71) MEN1KMT2A
20-Hydroxyecdysone SCHEMBL9481370 1.00 MEN1 (0.71) MEN1KMT2A
20-Hydroxyecdysone SCHEMBL8193574 1.00 MEN1 (0.71) MEN1KMT2A
20-Hydroxyecdysone SCHEMBL6243068 1.00 MEN1 (0.71) MEN1KMT2A
20-Hydroxyecdysone SCHEMBL8193572 1.00 MEN1 (0.71) MEN1KMT2A
20-Hydroxyecdysone SCHEMBL990951 1.00 MEN1 (0.71) MEN1KMT2A
20-Hydroxyecdysone SCHEMBL22087 1.00 MEN1 (0.71) MEN1KMT2A
20-Hydroxyecdysone SCHEMBL8861138 1.00 MEN1 (0.71) MEN1KMT2A
20-Hydroxyecdysone SCHEMBL8861142 1.00 MEN1 (0.71) MEN1KMT2A
20-Hydroxyecdysone SCHEMBL3043993 1.00 MEN1 (0.71) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11542295-B2 Use of 20-hydroxyecdysone and the derivatives thereof in the treatment of myopathies BIOPHYTIS (FR) 2023-01-03 — — US disclosed
EP-2995310-B1 Compositions for the treatment of overtraining syndrome SHI RES & DEVELOPMENT AB (SE) 2021-11-03 — — EP disclosed
US-20200179407-A1 USE OF 20-HYDROXYECDYSONE AND THE DERIVATIVES THEREOF IN THE TREATMENT OF MYOPATHIES BIOPHYTIS (FR) 2020-06-11 — — US disclosed
US-10316056-B2 Chemical compounds and use thereof for improving muscular quality BIOPHYTIS (FR) 2019-06-11 — — US disclosed
US-9938315-B2 Chemical compounds and use thereof for improving muscular quality BIOPHYTIS (FR) 2018-04-10 — — US disclosed
US-20170252389-A1 COMPOSITIONS FOR THE TREATMENT OF OVERTRAINING SYNDROME SHI RESEARCH & DEVELOPMENT AB (SE) 2017-09-07 — — US disclosed
EP-2995310-A1 Compositions for the treatment of overtraining syndrome Swedish Herbal Institute Research & Development AB (SE) 2016-03-16 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11542295-B2 Use of 20-hydroxyecdysone and the derivatives thereof in the treatment of myopathies MUSK, MTPN, MYLK2 MEN1 2545/4885KMT2A 2647/4885
US-10316056-B2 Chemical compounds and use thereof for improving muscular quality CPT1B, PYGM, GYS1 MEN1 4051/4885KMT2A 1396/4885
US-20200179407-A1 USE OF 20-HYDROXYECDYSONE AND THE DERIVATIVES THEREOF IN THE TREATMENT OF MYOPATHIES MUSK, MTPN, MYLK2 MEN1 2545/4885KMT2A 2647/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback