20-Hydroxyecdysone

20-Hydroxyecdysone

SCHEMBL22087

CC(C)(O)CCC(O)[C@](C)(O)[C@H]1CC[C@@]2(O)C3=CC(=O)[C@@H]4C[C@@H](O)[C@@H](O)C[C@]4(C)[C@H]3CC[C@]12C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.71
▸ KMT2A Q03164 1/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
20-Hydroxyecdysone SCHEMBL20033388 1.00 MEN1 (0.71) MEN1KMT2A
20-Hydroxyecdysone SCHEMBL9481370 1.00 MEN1 (0.71) MEN1KMT2A
20-Hydroxyecdysone SCHEMBL8193574 1.00 MEN1 (0.71) MEN1KMT2A
20-Hydroxyecdysone SCHEMBL6243068 1.00 MEN1 (0.71) MEN1KMT2A
20-Hydroxyecdysone SCHEMBL8193572 1.00 MEN1 (0.71) MEN1KMT2A
20-Hydroxyecdysone SCHEMBL990951 1.00 MEN1 (0.71) MEN1KMT2A
20-Hydroxyecdysone SCHEMBL8861138 1.00 MEN1 (0.71) MEN1KMT2A
20-Hydroxyecdysone SCHEMBL17580332 1.00 MEN1 (0.71) MEN1KMT2A
20-Hydroxyecdysone SCHEMBL8861142 1.00 MEN1 (0.71) MEN1KMT2A
20-Hydroxyecdysone SCHEMBL3043993 1.00 MEN1 (0.71) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1311 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260060962-A1 METHODS AND AGENTS THAT STIMULATE MITOCHONDRIAL TURNOVER FOR TREATING DISEASE CAPACITY BIO INC (US) 2026-03-05 — — US claimed
US-12551495-B2 Phytoecdysones and derivatives thereof for use in treating disordered respiratory function on viral infection BIOPHYTIS (FR) 2026-02-17 — — US claimed
EP-4482481-B1 COMPOUNDS FOR USE IN THE TREATMENT OF DYSTROPHINOPATHIES SOM INNOVATION BIOTECH S A (ES) 2025-11-12 — — EP claimed
EP-4637780-A1 PHYTOECDYSONES FOR USE IN THE TREATMENT OF INFLAMMATORY RESPIRATORY DISEASES Biophytis (FR) 2025-10-29 — — EP claimed
US-12440500-B2 Phytoecdysones and the derivatives thereof for use in the treatment of neuromuscular diseases BIOPHYTIS (FR) 2025-10-14 — — US claimed
EP-3758709-B1 PHYTOECDYSONES FOR USE IN THE PREVENTION OF MUSCLE STRENGTH LOSS DURING IMMOBILISATION BIOPHYTIS (FR) 2025-07-09 — — EP claimed
WO-2025132808-A1 COMPOSITIONS OF PHYTOECDYSONES FOR INTRANASAL ADMINISTRATION BIOPHYTIS (FR) 2025-06-26 — — WO claimed
US-20250207127-A1 PHYTOECDYSONES AND/OR 20-HYDROXYECDYSONE DERIVATIVES IN COMBINATION WITH AN ACTIVE INGREDIENT FOR RESTORING SMN EXPRESSION, FOR USE IN THE TREATMENT OF SPINAL MUSCULAR ATROPHY KREOS CAPITAL VI (UK) LIMITED (GB) 2025-06-26 — — US claimed
US-20250152567-A1 COMPOUNDS FOR USE IN THE TREATMENT OF DYSTROPHINOPATHIES REGENTS OF THE UNIVERSITY OF MINNESOTA 2025-05-15 — — US claimed
CN-115963199-B Quantitative detection method and application of steroid hormone in human/animal body fluid 上海鹿明生物科技有限公司 2025-04-29 — — CN claimed
WO-2001062780-A1 GENE EXPRESSION SYSTEM BASED ON CHIMERIC RECEPTORS THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 2001-08-30 — — WO claimed
EP-1112360-A1 ECDYSONE RECEPTORS AND METHODS FOR THEIR USE PIONEER HI-BRED INTERNATIONAL, INC. (US) 2001-07-04 — — EP claimed
EP-1018885-A1 INSECTICIDAL ENZYMES Mycogen Corporation (US) 2000-07-19 — — EP claimed
WO-2000015791-A1 ECDYSONE RECEPTORS AND METHODS FOR THEIR USE PIONEER HI-BRED INTERNATIONAL, INC. (US) 2000-03-23 — — WO claimed
EP-0914610-A1 SCREEN FOR ECDYSONE RECEPTOR LIGANDS AMERICAN CYANAMID COMPANY (US) 1999-05-12 — — EP claimed
WO-1997045731-A9 SCREEN FOR ECDYSONE RECEPTOR LIGANDS — 1998-03-19 — — WO claimed
WO-1997045731-A1 SCREEN FOR ECDYSONE RECEPTOR LIGANDS AMERICAN CYANAMID COMPANY (US) 1997-12-04 — — WO claimed
WO-1997020469-A1 INSECTICIDAL ENZYMES MYCOGEN CORPORATION (US) 1997-06-12 — — WO claimed
EP-0740930-A1 BLOOD FLOW IMPROVER AND COSMETIC POLA CHEMICAL INDUSTRIES, INC. (JP) 1996-11-06 — — EP claimed
EP-0120799-A1 Medicament and vaccine against helminth parasitization derived from an ecdysteroid compound Société Anonyme dite: IMMUNOTECH (FR) 1984-10-03 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250152567-A1 COMPOUNDS FOR USE IN THE TREATMENT OF DYSTROPHINOPATHIES MTPN, UTRN, TTN MEN1 4594/4885KMT2A 3665/4885
US-12440500-B2 Phytoecdysones and the derivatives thereof for use in the treatment of neuromuscular diseases SMN1; SMN2, PMP22, MUSK MEN1 2067/4885KMT2A 2482/4885
US-20250207127-A1 PHYTOECDYSONES AND/OR 20-HYDROXYECDYSONE DERIVATIVES IN COMBINATION WITH AN ACTIVE INGREDIENT FOR RESTORING SMN EXPRESSION, FOR USE IN THE TREATMENT OF SPINAL MUSCULAR ATROPHY SMN1; SMN2, PMP22, RBM17 MEN1 2048/4885KMT2A 1119/4885
US-20260060962-A1 METHODS AND AGENTS THAT STIMULATE MITOCHONDRIAL TURNOVER FOR TREATING DISEASE MDH2, NLN, PINK1 MEN1 1373/4885KMT2A 1892/4885
US-12551495-B2 Phytoecdysones and derivatives thereof for use in treating disordered respiratory function on viral infection ACE2, TMPRSS2, ACE MEN1 4399/4885KMT2A 3597/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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